Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 3/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | IL1B | P01584 | 2/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | SMO | Q99835 | 2/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 6/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26435657 | 0.93 | NLRP3 (0.43) | NLRP3KCNH2IL1BTNFSMO | |
| SCHEMBL26436151 | 0.91 | NLRP3 (0.44) | NLRP3KCNH2IL1BTNFSMO | |
| SCHEMBL26435052 | 0.87 | NLRP3 (0.47) | NLRP3KCNH2IL1BTNFKDM4E | |
| SCHEMBL26435893 | 0.85 | KCNH2 (0.48) | NLRP3KCNH2IL1BKAT2BJAK2 | |
| SCHEMBL26435322 | 0.84 | NLRP3 (0.44) | NLRP3KCNH2IL1BTNFSMO | |
| SCHEMBL26436167 | 0.83 | NLRP3 (0.35) | NLRP3IL1BTNFSMOKAT2B | |
| SCHEMBL26436028 | 0.82 | NLRP3 (0.52) | NLRP3KCNH2IL1BKAT2BJAK2 | |
| SCHEMBL26435635 | 0.81 | NLRP3 (0.57) | NLRP3KCNH2IL1BTNF | |
| SCHEMBL26436168 | 0.80 | IL1B (0.48) | NLRP3IL1BTNFKAT2BKDM4E | |
| SCHEMBL30375557 | 0.80 | KCNH2 (0.48) | NLRP3KCNH2IL1BKAT2BJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |