Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK13 | O15264 | 3/20 | 0.57 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.57 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.57 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.51 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | NGLY1 | Q96IV0 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27718639 | 0.85 | MAPK13 (0.59) | MAPK13MAPK12MAPK11MAPK14AKR1C3 | |
| SCHEMBL23448650 | 0.85 | KMT2A (0.50) | MAPK13MAPK12MAPK11MAPK14AKR1C3 | |
| SCHEMBL26436184 | 0.85 | MAPT (0.57) | MAPK13MAPK12MAPK11MAPK14AKR1C3 | |
| SCHEMBL8618268 | 0.83 | CASP3 (0.53) | MAPK13MAPK12MAPK11MAPK14AKR1C3 | |
| SCHEMBL23896576 | 0.81 | MAPK13 (0.67) | MAPK13MAPK12MAPK11MAPK14AKR1C3 | |
| SCHEMBL28472949 | 0.80 | AKR1C3 (0.64) | AKR1C3AKR1C2MAPTGFERNGLY1 | |
| SCHEMBL2000058 | 0.80 | KMT2A (0.63) | MAPTMEN1KMT2APOLBGFER | |
| SCHEMBL1706351 | 0.79 | CYP1A2 (0.47) | AKR1C3AKR1C2CYP1A2MAPTMEN1 | |
| SCHEMBL9691004 | 0.79 | CYP1A2 (0.47) | AKR1C3AKR1C2CYP1A2MAPTMEN1 | |
| SCHEMBL9141154 | 0.79 | MAPT (0.51) | MAPK13MAPK12MAPK11MAPK14AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
| US-20230127046-A1 | G9a INHIBITOR | RIKEN (JP) | 2023-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230127046-A1 | G9a INHIBITOR | EZH2, BMI1, DOT1L | MAPK13 2587/4885MAPK12 2543/4885MAPK11 2298/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.