SCHEMBL26436233

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL26436202	0.86	CFTR (0.44)	TAS2R14L3MBTL1ALDH1A1KMT2A
	SCHEMBL23448650	0.78	KMT2A (0.50)	AKR1C3AKR1C2MEN1ALDH1A1LMNA
	SCHEMBL30828569	0.78	MAPT (0.56)	L3MBTL1MEN1ALDH1A1PKMKMT2A
	SCHEMBL12893520	0.75	ALDH1A1 (0.50)	AKR1C3AKR1C2MEN1ALDH1A1LMNA
	SCHEMBL29151820	0.74	MAPT (0.51)	TAS2R14AKR1C3AKR1C2MEN1ALDH1A1
	SCHEMBL14325837	0.73	CYP1A2 (0.50)	TAS2R14L3MBTL1MEN1LMNACYP1A2
	SCHEMBL30017034	0.72	KDM4C (0.53)	SORT1L3MBTL1MEN1ALDH1A1DHODH
	SCHEMBL115907	0.72	KDM4C (0.53)	SORT1L3MBTL1MEN1ALDH1A1DHODH
	SCHEMBL1887153	0.71	NAPRT (0.64)	L3MBTL1TYK2JAK2
	SCHEMBL9431654	0.71	L3MBTL1 (0.55)	TAS2R14L3MBTL1MEN1CYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.