Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | PPM1D | O15297 | 3/20 | 0.49 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.49 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.49 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.47 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14420824 | 0.82 | LOXL2 (0.58) | LOXL2HIF1APPM1DCYP4F2CYP4A11 | |
| SCHEMBL15761754 | 0.80 | HIF1A (0.58) | LOXL2HIF1APPM1DCYP4F2CYP4A11 | |
| SCHEMBL15761746 | 0.78 | HIF1A (0.60) | LOXL2HIF1APPM1DCYP4F2CYP4A11 | |
| SCHEMBL15755934 | 0.77 | HIF1A (0.58) | LOXL2HIF1APPM1DCYP4F2CYP4A11 | |
| SCHEMBL29451790 | 0.77 | LOXL2 (1.00) | LOXL2HIF1ACYP4F2CYP4A11SLC7A5 | |
| SCHEMBL307892 | 0.77 | LOXL2 (1.00) | LOXL2HIF1ACYP4F2CYP4A11SLC7A5 | |
| SCHEMBL15761766 | 0.76 | HIF1A (0.54) | LOXL2HIF1APPM1DCYP4F2CYP4A11 | |
| SCHEMBL1180032 | 0.76 | LOXL2 (0.53) | LOXL2HIF1APPM1DCYP4F2CYP4A11 | |
| Hydrochloric Acid SCHEMBL307891 | 0.75 | LOXL2 (0.97) | LOXL2HIF1ACYP4F2CYP4A11SLC7A5 | |
| Hydrochloric Acid SCHEMBL307062 | 0.75 | LOXL2 (0.97) | LOXL2HIF1ACYP4F2CYP4A11SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069770-A1 | NOVEL HOST-TARGETED PAN-RESPIRATORY ANTIVIRAL SMALL MOLECULE THERAPEUTICS | PROSETTA BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |