SCHEMBL26436309 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	NLRP3	Q96P20	6/20	0.61

▸	CSNK2A2	P19784	2/20	0.39

▸	CSNK2B	P67870	2/20	0.39

▸	CSNK2A1	P68400	2/20	0.39

▸	ROCK2	O75116	5/20	0.38

▸	IL1B	P01584	4/20	0.38

▸	GABRA5	P31644	1/20	0.37

▸	ROCK1	Q13464	1/20	0.37

▸	PIK3CD	O00329	2/20	0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL26436315	0.93	NLRP3 (0.60)	NLRP3CSNK2A2CSNK2BCSNK2A1ROCK2
SCHEMBL26437605	0.89	NLRP3 (0.55)	NLRP3IL1BGABRA5PIK3CD
SCHEMBL26436334	0.88	NLRP3 (0.46)	NLRP3ROCK2IL1BPIK3CD
SCHEMBL26436297	0.86	NLRP3 (0.81)	NLRP3IL1B
SCHEMBL26436765	0.84	NLRP3 (0.52)	NLRP3IL1BGABRA5PIK3CD
SCHEMBL26436319	0.83	NLRP3 (0.60)	NLRP3CSNK2A2CSNK2BCSNK2A1ROCK2
SCHEMBL29275846	0.83	NLRP3 (0.81)	NLRP3IL1B
SCHEMBL30214151	0.83	NLRP3 (0.81)	NLRP3IL1B
SCHEMBL26437146	0.81	NLRP3 (0.58)	NLRP3GABRA5
SCHEMBL26437428	0.81	NLRP3 (0.50)	NLRP3IL1BGABRA5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023066377-A1	NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF	索智生物科技（浙江）有限公司	2023-04-27	—	—	WO	disclosed