Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 14/20 | 0.50 |
| ▸ | IL1B | P01584 | 9/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TNF | P01375 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437431 | 0.92 | NLRP3 (0.49) | NLRP3IL1BKCNH2TNF | |
| SCHEMBL26437412 | 0.91 | IL1B (0.53) | NLRP3IL1BKCNH2TNF | |
| SCHEMBL26437398 | 0.89 | IL1B (0.55) | NLRP3IL1BKCNH2TNF | |
| SCHEMBL26437605 | 0.86 | NLRP3 (0.55) | NLRP3IL1BGABRA5 | |
| SCHEMBL26436765 | 0.85 | NLRP3 (0.52) | NLRP3IL1BGABRA5 | |
| SCHEMBL26437286 | 0.84 | NLRP3 (0.49) | NLRP3IL1BGABRA5 | |
| SCHEMBL26437414 | 0.83 | NLRP3 (0.66) | NLRP3IL1B | |
| SCHEMBL26772355 | 0.83 | NLRP3 (0.66) | NLRP3IL1B | |
| SCHEMBL26437422 | 0.83 | IL1B (0.52) | NLRP3IL1BKCNH2TNF | |
| SCHEMBL26436309 | 0.81 | NLRP3 (0.61) | NLRP3IL1BGABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |