SCHEMBL26436623

SCHEMBL26436623

CCCN1C(=O)c2c(-c3ccc(C)s3)sc(-c3ccc(C)s3)c2C1=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 11/20 0.44
MAPT P10636 7/20 0.44
KMT2A Q03164 7/20 0.44
MEN1 O00255 6/20 0.44
NPSR1 Q6W5P4 1/20 0.44
HPGD P15428 3/20 0.42
LMNA P02545 2/20 0.42
POLB P06746 2/20 0.42
NPC1 O15118 1/20 0.42
TNFRSF1A P19438 1/20 0.42
MAPK1 P28482 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
HSF1 Q00613 4/20 0.39
CYP1A2 P05177 2/20 0.36
CYP3A4 P08684 2/20 0.36
CYP2C19 P33261 2/20 0.36
CYP2C9 P11712 1/20 0.36
GAA P10253 2/20 0.36
CISD1 Q9NZ45 2/20 0.35
MAOA P21397 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26436615 0.92 ALDH1A1 (0.39) ALDH1A1MAPTKMT2AMEN1NPSR1
SCHEMBL14725895 0.82 HSF1 (0.39) ALDH1A1HPGDHSF1CYP3A4HSD17B10
SCHEMBL15979504 0.82 MAPT (0.37) ALDH1A1MAPTKMT2AMEN1NPSR1
SCHEMBL19758058 0.80 HSF1 (0.38) ALDH1A1HSF1
SCHEMBL25450938 0.74 USP2 (0.41) ALDH1A1MAPTKMT2AMEN1NPSR1
SCHEMBL14716693 0.73 PTGS1 (0.41) ALDH1A1HPGDTNFRSF1ACYP3A4HSD17B10
SCHEMBL14716528 0.73 PTGS1 (0.41) ALDH1A1HPGDTNFRSF1ACYP3A4HSD17B10
SCHEMBL16307271 0.72 HSF1 (0.34) ALDH1A1MAPTKMT2AMEN1NPSR1
SCHEMBL25450978 0.72 HSPA1A (0.41) ALDH1A1MAPTKMT2AMEN1NPSR1
SCHEMBL18325069 0.71 HSF1 (0.35) ALDH1A1MAPTHPGDLMNAHSF1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023068017-A1 ORGANIC SEMICONDUCTOR MATERIAL 東洋紡株式会社 2023-04-27 WO disclosed