Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 10/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 6/20 | 0.33 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.33 |
| ▸ | SETD2 | Q9BYW2 | 3/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.30 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.30 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.30 |
| ▸ | CCR3 | P51677 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26435061 | 0.95 | CRBN (0.35) | CRBNDDB1GSPT1SETD2ALDH1A1 | |
| SCHEMBL26436128 | 0.90 | FASN (0.33) | CRBNDDB1GSPT1SETD2FFAR4 | |
| SCHEMBL26435942 | 0.90 | GRM4 (0.35) | CRBNDDB1GSPT1SETD2FFAR4 | |
| SCHEMBL26436052 | 0.86 | POLB (0.33) | CCR3POLB | |
| SCHEMBL30407993 | 0.86 | DDB1 (0.40) | CRBNDDB1GSPT1 | |
| SCHEMBL26436839 | 0.86 | DDB1 (0.40) | CRBNDDB1GSPT1 | |
| SCHEMBL26436127 | 0.85 | DDB1 (0.34) | CRBNDDB1GSPT1 | |
| SCHEMBL26434735 | 0.84 | CRBN (0.36) | CRBNDDB1POLB | |
| SCHEMBL26133407 | 0.84 | CRBN (0.52) | CRBNDDB1GSPT1 | |
| SCHEMBL26436350 | 0.83 | CRBN (0.34) | CRBNDDB1GSPT1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069708-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |