Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 6/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.34 |
| ▸ | GSPT1 | P15170 | 1/20 | 0.34 |
| ▸ | FASN | P49327 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.31 |
| ▸ | PREP | P48147 | 1/20 | 0.31 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.31 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.31 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26436128 | 0.89 | FASN (0.33) | DDB1CRBNGSPT1FASN | |
| SCHEMBL26435061 | 0.88 | CRBN (0.35) | DDB1CRBNGSPT1 | |
| SCHEMBL26436839 | 0.87 | DDB1 (0.40) | DDB1CRBNGSPT1 | |
| SCHEMBL30407993 | 0.87 | DDB1 (0.40) | DDB1CRBNGSPT1 | |
| SCHEMBL26132018 | 0.86 | CRBN (0.36) | DDB1CRBNGSPT1 | |
| SCHEMBL26436126 | 0.86 | RIPK1 (0.34) | DDB1CRBNGSPT1FASN | |
| SCHEMBL26436842 | 0.85 | CRBN (0.33) | DDB1CRBNGSPT1 | |
| SCHEMBL26133407 | 0.83 | CRBN (0.52) | DDB1CRBNGSPT1 | |
| SCHEMBL26435942 | 0.82 | GRM4 (0.35) | DDB1CRBNGSPT1 | |
| SCHEMBL26434735 | 0.82 | CRBN (0.36) | DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069708-A1 | COMPOUNDS THAT MEDIATE PROTEIN DEGRADATION AND USES THEREOF | MONTE ROSA THERAPEUTICS, INC. (US) | 2023-04-27 | — | — | WO | disclosed |