Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.57 |
| ▸ | JUN | P05412 | 4/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 4/20 | 0.42 |
| ▸ | CDK2 | P24941 | 3/20 | 0.42 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.42 |
| ▸ | JAK2 | O60674 | 2/20 | 0.41 |
| ▸ | JAK3 | P52333 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | PRKCI | P41743 | 2/20 | 0.38 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437146 | 0.92 | NLRP3 (0.58) | NLRP3JUNMAPK8MAPK9CDK2 | |
| SCHEMBL26437133 | 0.90 | NLRP3 (0.46) | NLRP3JUNMAPK8MAPK9CDK2 | |
| SCHEMBL26435312 | 0.88 | NLRP3 (0.53) | NLRP3JUNMAPK8MAPK9CDK2 | |
| SCHEMBL26436531 | 0.88 | NLRP3 (0.55) | NLRP3JAK2JAK3PRKCI | |
| SCHEMBL26437596 | 0.87 | NLRP3 (0.47) | NLRP3JUNMAPK8MAPK9CDK2 | |
| SCHEMBL26435064 | 0.86 | NLRP3 (0.48) | NLRP3JUNMAPK8MAPK9CDK2 | |
| SCHEMBL30214821 | 0.83 | NLRP3 (0.81) | NLRP3CDK2CHEK1 | |
| SCHEMBL29275831 | 0.83 | NLRP3 (0.81) | NLRP3CDK2CHEK1 | |
| SCHEMBL29276147 | 0.83 | NLRP3 (0.81) | NLRP3CDK2CHEK1 | |
| SCHEMBL26437132 | 0.83 | NLRP3 (0.47) | NLRP3JUNMAPK8MAPK9CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |