Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 12/20 | 0.55 |
| ▸ | IL1B | P01584 | 11/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.43 |
| ▸ | CCNK | O75909 | 1/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | CDK9 | P50750 | 1/20 | 0.43 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437268 | 0.90 | NLRP3 (0.68) | NLRP3IL1B | |
| SCHEMBL25856253 | 0.85 | NLRP3 (0.53) | NLRP3IL1B | |
| SCHEMBL30374870 | 0.85 | IL1B (0.57) | NLRP3IL1B | |
| SCHEMBL26093401 | 0.85 | IL1B (0.57) | NLRP3IL1B | |
| SCHEMBL26093410 | 0.85 | IL1B (0.57) | NLRP3IL1B | |
| SCHEMBL30055336 | 0.85 | IL1B (0.70) | NLRP3IL1B | |
| SCHEMBL26434252 | 0.85 | IL1B (0.56) | NLRP3IL1B | |
| SCHEMBL26089569 | 0.85 | IL1B (0.70) | NLRP3IL1B | |
| SCHEMBL26089562 | 0.85 | IL1B (0.70) | NLRP3IL1B | |
| SCHEMBL26437261 | 0.84 | NLRP3 (0.46) | NLRP3IL1BCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |