Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 13/20 | 0.49 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | JUN | P05412 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.37 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | IL1B | P01584 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437287 | 0.92 | NLRP3 (0.49) | NLRP3JUNMAPK8MAPK9CDK2 | |
| SCHEMBL26437261 | 0.91 | NLRP3 (0.46) | NLRP3GABRA5JUNMAPK8MAPK9 | |
| SCHEMBL26093692 | 0.89 | NLRP3 (0.45) | NLRP3IL1B | |
| SCHEMBL30380020 | 0.89 | NLRP3 (0.45) | NLRP3IL1B | |
| SCHEMBL26093685 | 0.89 | NLRP3 (0.45) | NLRP3IL1B | |
| SCHEMBL26446966 | 0.86 | NLRP3 (0.56) | NLRP3JUNMAPK8MAPK9CDK2 | |
| SCHEMBL26437605 | 0.85 | NLRP3 (0.55) | NLRP3GABRA5KAT2BIL1B | |
| SCHEMBL26437428 | 0.84 | NLRP3 (0.50) | NLRP3GABRA5IL1B | |
| SCHEMBL26437268 | 0.84 | NLRP3 (0.68) | NLRP3IL1B | |
| SCHEMBL26437277 | 0.83 | NLRP3 (0.42) | NLRP3JUNMAPK8MAPK9CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |