Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.54 |
| ▸ | SUV39H2 | Q9H5I1 | 6/20 | 0.39 |
| ▸ | QPCT | Q16769 | 2/20 | 0.38 |
| ▸ | IDH1 | O75874 | 2/20 | 0.38 |
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.38 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13363829 | 0.82 | QPCT (0.49) | HRH3SUV39H2QPCT | |
| SCHEMBL26438297 | 0.82 | HRH3 (0.47) | HRH3SUV39H2QPCT | |
| SCHEMBL3324022 | 0.80 | HRH3 (0.46) | HRH3SUV39H2QPCT | |
| SCHEMBL26437457 | 0.80 | HRH3 (0.49) | HRH3SUV39H2QPCTPIK3C3 | |
| SCHEMBL13336404 | 0.80 | HRH3 (0.49) | HRH3SUV39H2QPCTPIK3C3 | |
| SCHEMBL26437436 | 0.80 | HRH3 (0.49) | HRH3SUV39H2QPCTPIK3C3 | |
| SCHEMBL26437835 | 0.76 | HRH3 (0.47) | HRH3SUV39H2QPCTPIK3C3 | |
| SCHEMBL26437646 | 0.76 | HRH3 (0.54) | HRH3SUV39H2QPCTPIK3C3 | |
| SCHEMBL26439865 | 0.75 | HRH3 (0.51) | HRH3SUV39H2QPCTPIK3C3 | |
| SCHEMBL16212221 | 0.75 | TLR9 (0.53) | SUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066204-A1 | SIK INHIBITOR, COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2023-04-27 | — | — | WO | disclosed |