Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 6/20 | 0.45 |
| ▸ | CD63 | P08962 | 1/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.39 |
| ▸ | SUV39H2 | Q9H5I1 | 1/20 | 0.37 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26437835 | 0.79 | HRH3 (0.47) | HRH3SUV39H2AOC3F10PIK3C3 | |
| SCHEMBL26437992 | 0.78 | HRH3 (0.42) | HRH3SUV39H2AOC3F10PIK3C3 | |
| SCHEMBL13407684 | 0.76 | HRH3 (0.45) | HRH3SUV39H2AOC3F10 | |
| SCHEMBL13336404 | 0.74 | HRH3 (0.49) | HRH3SUV39H2AOC3F10PIK3C3 | |
| SCHEMBL26437457 | 0.74 | HRH3 (0.49) | HRH3SUV39H2AOC3F10PIK3C3 | |
| SCHEMBL26437436 | 0.74 | HRH3 (0.49) | HRH3SUV39H2AOC3F10PIK3C3 | |
| SCHEMBL26437555 | 0.73 | HRH3 (0.45) | SYKHRH3SUV39H2AOC3F10 | |
| SCHEMBL26438121 | 0.73 | HRH3 (0.41) | HRH3SUV39H2AOC3F10PIK3C3 | |
| SCHEMBL28276522 | 0.71 | ADORA2A (0.54) | SYKCD63CHEK1ADORA2AADORA1 | |
| SCHEMBL23104529 | 0.71 | ADORA2A (0.49) | SYKCD63CHEK1ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066204-A1 | SIK INHIBITOR, COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2023-04-27 | — | — | WO | disclosed |