Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 6/20 | 0.51 |
| ▸ | WNT3A | P56704 | 6/20 | 0.51 |
| ▸ | ROCK2 | O75116 | 4/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.49 |
| ▸ | NOS1 | P29475 | 3/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264384 | 1.00 | RAB9A (0.57) | RAB9AMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL16617733 | 0.82 | CTNNB1 (0.56) | RAB9AMAPTCTNNB1WNT3AROCK2 | |
| SCHEMBL12601125 | 0.80 | ROCK2 (0.51) | RAB9AMAPTCTNNB1WNT3AROCK2 | |
| SCHEMBL774795 | 0.80 | ROCK2 (0.51) | RAB9AMAPTCTNNB1WNT3AROCK2 | |
| SCHEMBL774794 | 0.80 | ROCK2 (0.51) | RAB9AMAPTCTNNB1WNT3AROCK2 | |
| SCHEMBL29521387 | 0.79 | ROCK2 (0.64) | RAB9AMAPTCTNNB1WNT3AROCK2 | |
| SCHEMBL122504 | 0.79 | ROCK2 (0.64) | RAB9AMAPTCTNNB1WNT3AROCK2 | |
| SCHEMBL14738116 | 0.79 | CTNNB1 (0.54) | RAB9AMAPTCTNNB1WNT3AROCK2 | |
| SCHEMBL1210126 | 0.77 | CTNNB1 (0.43) | RAB9AMAPTCTNNB1WNT3AROCK2 | |
| SCHEMBL1210124 | 0.77 | CTNNB1 (0.43) | RAB9AMAPTCTNNB1WNT3AROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8134004-B2 | Substituted N-bicyclicalkyl bicycliccarboxyamide compounds | PFIZER INC. (US) | 2012-03-13 | — | — | US | disclosed |
| US-20090253740-A1 | SUBSTITUTED N-BICYCLICALKYL BICYCLICCARBOXYAMIDE COMPOUNDS | PFIZER INC | 2009-10-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090253740-A1 | SUBSTITUTED N-BICYCLICALKYL BICYCLICCARBOXYAMIDE COMPOUNDS | OPRL1, CNR1, TRPV1 | RAB9A 1112/4885MAPT 4405/4885CYP1A2 882/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.