Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.52 |
| ▸ | IL1B | P01584 | 8/20 | 0.45 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 6/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.34 |
| ▸ | COMT | P21964 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26435635 | 0.91 | NLRP3 (0.57) | KCNH2NLRP3IL1BTNFHCRTR1 | |
| SCHEMBL30375062 | 0.86 | NLRP3 (0.68) | KCNH2NLRP3IL1BTNFHCRTR1 | |
| SCHEMBL26435693 | 0.86 | NLRP3 (0.68) | KCNH2NLRP3IL1BTNFHCRTR1 | |
| SCHEMBL26438939 | 0.86 | NLRP3 (0.68) | KCNH2NLRP3IL1BTNFHCRTR1 | |
| SCHEMBL26093704 | 0.86 | NLRP3 (0.68) | KCNH2NLRP3IL1BTNFHCRTR1 | |
| SCHEMBL26437103 | 0.85 | NLRP3 (0.54) | KCNH2NLRP3IL1BTNFHCRTR1 | |
| SCHEMBL24855502 | 0.83 | KCNH2 (0.55) | KCNH2NLRP3IL1BTNFHCRTR1 | |
| SCHEMBL30181295 | 0.83 | KCNH2 (0.55) | KCNH2NLRP3IL1BTNFHCRTR1 | |
| SCHEMBL30181105 | 0.83 | KCNH2 (0.55) | KCNH2NLRP3IL1BTNFHCRTR1 | |
| SCHEMBL30181438 | 0.83 | KCNH2 (0.55) | KCNH2NLRP3IL1BTNFHCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066377-A1 | NITROGEN-CONTAINING COMPOUND, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 索智生物科技（浙江）有限公司 | 2023-04-27 | — | — | WO | disclosed |