Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.42 |
| ▸ | DUT | P33316 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.39 |
| ▸ | TK1 | P04183 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | EDNRB | P24530 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.32 |
| ▸ | MLNR | O43193 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4186770 | 0.93 | DUT (0.44) | PLA2G2APLA2G10PLA2G1BPLA2G5DUT | |
| SCHEMBL4186763 | 0.93 | DUT (0.44) | PLA2G2APLA2G10PLA2G1BPLA2G5DUT | |
| SCHEMBL13377619 | 0.83 | DUT (0.41) | PLA2G2APLA2G10PLA2G1BPLA2G5DUT | |
| SCHEMBL5699551 | 0.82 | DUT (0.40) | PLA2G2APLA2G10PLA2G1BPLA2G5DUT | |
| SCHEMBL4763266 | 0.82 | DUT (0.40) | PLA2G2APLA2G10PLA2G1BPLA2G5DUT | |
| SCHEMBL4192567 | 0.81 | DUT (0.39) | PLA2G2APLA2G10PLA2G1BPLA2G5DUT | |
| SCHEMBL4192561 | 0.81 | DUT (0.39) | PLA2G2APLA2G10PLA2G1BPLA2G5DUT | |
| SCHEMBL8195323 | 0.81 | PLA2G2A (0.53) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8356181 | 0.81 | PLA2G2A (0.53) | PLA2G2APLA2G10PLA2G1BPLA2G5 | |
| SCHEMBL8353837 | 0.81 | PLA2G2A (0.53) | PLA2G2APLA2G10PLA2G1BPLA2G5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192984-A1 | N-DESMETHYL RUBOXISTAURIN AS KINASE INHIBITOR | 4M THERAPEUTICS INC. (US) | 2023-10-05 | — | — | WO | disclosed |