Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 6/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.51 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.38 |
| ▸ | SUV39H2 | Q9H5I1 | 2/20 | 0.37 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | QPCT | Q16769 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26438459 | 0.85 | HRH3 (0.65) | OGAHRH3TLR9TLR7AOC3 | |
| SCHEMBL31696699 | 0.78 | MEN1 (0.51) | HRH3AOC3F10SUV39H2 | |
| SCHEMBL26438620 | 0.76 | AOC3 (0.42) | OGAHRH3AOC3F10SUV39H2 | |
| SCHEMBL3785803 | 0.76 | HRH3 (0.50) | OGAHRH3AOC3F10SUV39H2 | |
| SCHEMBL26440146 | 0.74 | HRH3 (0.41) | OGAHRH3TLR9TLR7AOC3 | |
| SCHEMBL13407684 | 0.72 | HRH3 (0.45) | HRH3AOC3F10SUV39H2 | |
| SCHEMBL26438713 | 0.72 | TLR9 (0.48) | HRH3TLR9TLR7SUV39H2QPCT | |
| SCHEMBL26437646 | 0.70 | HRH3 (0.54) | HRH3AOC3F10SUV39H2PIK3C3 | |
| SCHEMBL26437884 | 0.69 | SUV39H2 (0.47) | HRH3AOC3F10SUV39H2 | |
| SCHEMBL19295993 | 0.69 | OGA (1.00) | OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023066204-A1 | SIK INHIBITOR, COMPOSITION THEREOF, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海美悦生物科技发展有限公司 | 2023-04-27 | — | — | WO | disclosed |