Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.55 |
| ▸ | GCGR | P47871 | 3/20 | 0.52 |
| ▸ | BRAF | P15056 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GALR3 | O60755 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.48 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2644096 | 0.90 | APOBEC3G (0.67) | APOBEC3GALDH1A1MEN1KMT2AHTT | |
| SCHEMBL2644079 | 0.85 | APOBEC3G (0.61) | APOBEC3GALDH1A1MEN1KMT2AHTT | |
| SCHEMBL2644453 | 0.84 | APOBEC3G (0.58) | APOBEC3GALDH1A1MEN1KMT2AHTT | |
| SCHEMBL2648027 | 0.83 | APOBEC3G (0.57) | APOBEC3GALDH1A1MEN1KMT2AHTT | |
| SCHEMBL2644163 | 0.81 | APOBEC3G (0.56) | APOBEC3GALDH1A1MEN1KMT2AHTT | |
| SCHEMBL2644114 | 0.81 | GCGR (0.59) | APOBEC3GALDH1A1MEN1KMT2ARXFP1 | |
| SCHEMBL2643157 | 0.80 | APOBEC3G (0.55) | APOBEC3GALDH1A1MEN1KMT2AHTT | |
| SCHEMBL2643974 | 0.79 | ALDH1A1 (0.60) | APOBEC3GALDH1A1MEN1KMT2AHTT | |
| SCHEMBL2644182 | 0.79 | APOBEC3G (0.59) | APOBEC3GALDH1A1MEN1KMT2AHTT | |
| SCHEMBL2646542 | 0.78 | APOBEC3G (0.53) | APOBEC3GALDH1A1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097557-A1 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | DUFFY JOSEPH L (US) | 2004-05-20 | — | — | US | claimed |
| US-20040097557-A1 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | DUFFY JOSEPH L (US) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097557-A1 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | GLP1R, GPR119, GCGR | APOBEC3G 4604/4885ALDH1A1 2652/4885MEN1 902/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.