⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Cyclohexane SCHEMBL7261875 | 0.94 | POLB (0.46) | — | |
| SCHEMBL28385112 | 0.88 | TSHR (0.44) | — | |
| Trifluoroacetic Acid SCHEMBL30626645 | 0.85 | TSHR (0.45) | — | |
| Trifluoroacetic Acid SCHEMBL30626646 | 0.85 | TSHR (0.45) | — | |
| SCHEMBL174910 | 0.82 | NPC1 (0.49) | — | |
| SCHEMBL9752595 | 0.80 | L3MBTL1 (0.55) | — | |
| SCHEMBL6727933 | 0.79 | L3MBTL1 (0.47) | — | |
| SCHEMBL31043089 | 0.77 | — | — | |
| SCHEMBL7240177 | 0.77 | POLB (0.43) | — | |
| SCHEMBL2495415 | 0.77 | TP53 (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 150 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3513792-B9 | MORPHINAN DERIVATIVES FOR THE TREATMENT OF OPIOID DELTA RECEPTOR AGONIST-RELATED DISEASES | NIPPON CHEMIPHAR CO (JP) | 2024-07-10 | — | — | EP | claimed |
| CN-113292559-B | Morphinan derivatives | 日本化学药品株式会社 | 2024-04-02 | — | — | CN | claimed |
| EP-3513792-B1 | MORPHINAN DERIVATIVES FOR THE TREATMENT OF OPIOID DELTA RECEPTOR AGONIST-RELATED DISEASES | NIPPON CHEMIPHAR CO (JP) | 2024-03-27 | — | — | EP | claimed |
| CN-117567874-A | Bright yellow reactive dye and preparation method thereof | 湖北华丽染料工业有限公司 | 2024-02-20 | — | — | CN | claimed |
| CN-117122598-A | Use of morphinan derivatives in the treatment of opioid delta receptor agonist-related diseases | 日本化学药品株式会社 | 2023-11-28 | — | — | CN | claimed |
| CN-116997360-A | Pharmaceutical composition for treating or preventing stress-related disorders | 学校法人东京理科大学 | 2023-11-03 | — | — | CN | claimed |
| CN-110248658-B | Use of morphinan derivatives in the treatment of opioid delta receptor agonist-related diseases | 日本化学药品株式会社 | 2023-10-13 | — | — | CN | claimed |
| EP-3974430-A1 | MORPHINAN DERIVATIVE | Nippon Chemiphar Co., Ltd. (JP) | 2022-03-30 | — | — | EP | claimed |
| CN-108659571-B | Double-active-group yellow reactive dye for printing | 无锡润新染料有限公司 | 2020-04-03 | — | — | CN | claimed |
| EP-3612522-A1 | THERAPEUTIC COMPOUNDS | Celgene Quanticel Research, Inc. (US) | 2020-02-26 | — | — | EP | claimed |
| WO-2018195155-A1 | THERAPEUTIC COMPOUNDS | CELGENE QUANTICEL RESEARCH, INC. (US) | 2018-10-25 | — | — | WO | claimed |
| CN-105504872-A | Bright orange reactive dye as well as preparation method and application thereof | HUBEI HWALLE DYESTUFF IND CO LTD | 2016-04-20 | — | — | CN | claimed |
| US-5955568-A | REACTION OF AROMETIC TRICARBOXYLIC ACID ANHYDRIDE WITH AROMATIC DIAMINE TO YIELD DIIMIDEDICARBOXYLIC ACID, DISSOLVING AN ACYL HALOGENATION AGENT, COOLING AND COMPLEXING THEN REACTION WITH DIAMINE FOR POLYAMIDEIMIDE | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 1999-09-21 | — | — | US | claimed |
| EP-4665733-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | Bristol-Myers Squibb Company (US) | 2025-12-24 | — | — | EP | disclosed |
| EP-4551564-A2 | ONE-STEP SYNTHESIS OF BETA-ALKYLIDENE-GAMMA-LACTONES | The Scripps Research Institute (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2024173323-A1 | AMINO-SUBSTITUTED PYRROLOTRIAZINE DERIVATIVES AS INHIBITORS OF SGK1 | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-08-22 | — | — | WO | disclosed |
| EP-0246739-A2 | Macrolide compounds, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1987-11-25 | — | — | EP | disclosed |
| US-4361436-A | Composition for plant growth regulation | GAF CORPORATION (US) | 1982-11-30 | — | — | US | disclosed |
| US-4191555-A | HORMONE INHIBITORS | GAF CORPORATION (US) | 1980-03-04 | — | — | US | disclosed |
| US-3933886-A | HAIR DYE | HENKEL & CIE GMBH (DT) | 1976-01-20 | — | — | US | disclosed |