Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.38 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6727933 | 0.88 | L3MBTL1 (0.47) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL9752595 | 0.86 | L3MBTL1 (0.55) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL2495415 | 0.86 | TP53 (0.45) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL10764271 | 0.84 | ALDH1A1 (0.47) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL12096492 | 0.84 | ALDH1A1 (0.47) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL11613395 | 0.84 | ALDH1A1 (0.47) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL8778695 | 0.84 | ALDH1A1 (0.47) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL10767578 | 0.84 | ALDH1A1 (0.47) | NPC1MITFLMNATP53RAB9A | |
| Hydrochloric Acid SCHEMBL1933284 | 0.83 | ALDH1A1 (0.46) | NPC1MITFLMNATP53RAB9A | |
| SCHEMBL9394796 | 0.82 | L3MBTL1 (0.51) | NPC1MITFLMNATP53RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117897440-A | Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition | 株式会社LG化学 | 2024-04-16 | — | — | CN | claimed |
| US-20150148363-A1 | NEW AZACYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. | 2015-05-28 | — | — | US | claimed |
| US-20120041013-A1 | NEW AZACYCLIC COMPOUNDS | F. HOFFMANN-LA ROCHE AG (CH) | 2012-02-16 | — | — | US | claimed |
| EP-0093498-B1 | PHARMACEUTICAL COMPOSITIONS CONTAINING N-SUBSTITUTED-3-HYDROXYPYRID-2-ONE OR -4-ONE DERIVATIVES | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1986-11-26 | — | — | EP | claimed |
| CN-117897440-A | Method for screening solvent for extraction of polyvinyl chloride, method for recycling waste material, recycled polyvinyl chloride and composition | 株式会社LG化学 | 2024-04-16 | — | — | CN | disclosed |
| CN-111542557-B | Conjugated diene rubber | 日本瑞翁株式会社 | 2023-03-28 | — | — | CN | disclosed |
| CN-111868098-B | Method for producing conjugated diene rubber | 日本瑞翁株式会社 | 2022-12-23 | — | — | CN | disclosed |
| US-11497738-B2 | Di-substituted pyrazole compounds for the treatment of diseases | FGH BIOTECH, INC. (US) | 2022-11-15 | — | — | US | disclosed |
| CN-115348975-A | Conjugated diene polymer, method for producing conjugated diene polymer, conjugated diene polymer composition, and rubber composition | 旭化成株式会社 | 2022-11-15 | — | — | CN | disclosed |
| CN-110072861-B | Disubstituted pyrazoles for the treatment of diseases | FGH生物科技公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-114933676-A | Polyfunctional vinyl aromatic copolymer and process for producing the same, conjugated diene copolymer and composition thereof, crosslinked product, and tire member | 日铁化学材料株式会社 | 2022-08-23 | — | — | CN | disclosed |
| US-11339142-B2 | Di-substituted pyrazole compounds for the treatment of diseases | FGH BIOTECH, INC. (US) | 2022-05-24 | — | — | US | disclosed |
| EP-1249443-A2 | Process for the production of hydroxybenzoic acid benzyl esters | BAYER AG (DE) | 2002-10-16 | — | — | EP | disclosed |
| US-5245046-A | α-amino-indole-3-acetic acids useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents | THE UPJOHN COMPANY (US) | 1993-09-14 | — | — | US | disclosed |
| WO-1991009848-A1 | PYRIDINONES USEFUL AS ANTIATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | disclosed |
| EP-0417143-A1 | CYCLIC LACTAMS FOR CHOLESTEROL AND ATHEROSCLEROSIS CONTROL | THE UPJOHN COMPANY (US) | 1991-03-20 | — | — | EP | disclosed |
| EP-0375133-A1 | Alpha-amino-indole-3-acetic acids useful as anti-diabetic, anti-obesity and anti-atherosclerotic agents | THE UPJOHN COMPANY (US) | 1990-06-27 | — | — | EP | disclosed |
| WO-1990005721-A1 | ALPHA-AMINO-INDOLE-3-ACETIC ACIDS USEFUL AS ANTI-DIABETIC, ANTI-OBESITY AND ANTI-ATHEROSCLEROTIC AGENTS | THE UPJOHN COMPANY (US) | 1990-05-31 | — | — | WO | disclosed |
| WO-1989011856-A2 | CYCLIC LACTAMS FOR CHOLESTEROL AND ATHEROSCLEROSIS CONTROL | THE UPJOHN COMPANY (US) | 1989-12-14 | — | — | WO | disclosed |
| US-4361436-A | Composition for plant growth regulation | GAF CORPORATION (US) | 1982-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11339142-B2 | Di-substituted pyrazole compounds for the treatment of diseases | SREBF1, SREBF2, CYP27A1 | NPC1 74/4885MITF 1643/4885LMNA 1555/4885 |
| US-11497738-B2 | Di-substituted pyrazole compounds for the treatment of diseases | SREBF1, SREBF2, CYP27A1 | NPC1 74/4885MITF 1643/4885LMNA 1555/4885 |
| US-20120041013-A1 | NEW AZACYCLIC COMPOUNDS | LIPE, GPR119, LIPC | NPC1 620/4885MITF 1341/4885LMNA 999/4885 |
| US-20150148363-A1 | NEW AZACYCLIC COMPOUNDS | LIPE, GPR119, LIPC | NPC1 620/4885MITF 1341/4885LMNA 999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.