SCHEMBL2644490

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2645086	0.88	GCK (0.56)	GCK
	SCHEMBL2644091	0.87	GCK (0.40)	KMT2AMEN1GCKALDH1A1HPGD
	SCHEMBL643904	0.85	GCK (0.54)	KMT2AMEN1GCKALDH1A1HPGD
	SCHEMBL2643898	0.85	GCK (0.52)	KMT2AMEN1GCKALDH1A1HPGD
	SCHEMBL2644795	0.83	GCK (0.47)	KMT2AGCKALDH1A1HPGDL3MBTL1
	SCHEMBL2644101	0.83	GCK (0.45)	KMT2AMEN1GCKALDH1A1HPGD
	SCHEMBL644207	0.83	GCK (0.65)	GCKNPC1RAB9A
	SCHEMBL642785	0.82	ALDH1A1 (0.46)	GCKALDH1A1HPGDRXRAKDM4E
	SCHEMBL15780521	0.78	GCK (0.49)	KMT2AMEN1GCKALDH1A1HPGD
	SCHEMBL2643958	0.77	ALDH1A1 (0.43)	KMT2AMEN1GCKALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.