SCHEMBL642785

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15780545	0.91	HPGD (0.46)	ALDH1A1HPGDSMN1; SMN2GCKRXRA
	SCHEMBL643223	0.89	GCK (0.44)	ALDH1A1HPGDSMN1; SMN2GCKKCNH2
	SCHEMBL2643934	0.86	GCK (0.43)	ALDH1A1HPGDSMN1; SMN2GCKRXRA
	SCHEMBL644377	0.86	GCK (0.52)	ALDH1A1HPGDSMN1; SMN2GCKRXRA
	SCHEMBL2644207	0.85	LMNA (0.39)	GCKF10F2SLC6A2SLC6A4
	SCHEMBL2643446	0.85	SLC6A2 (0.42)	GCKKCNH2GAAF10F2
	SCHEMBL2645034	0.84	GCK (0.42)	ALDH1A1HPGDGCKKDM4EGLA
	SCHEMBL2643958	0.84	ALDH1A1 (0.43)	ALDH1A1HPGDSMN1; SMN2GCKRXRA
	SCHEMBL2643968	0.83	GCK (0.42)	ALDH1A1HPGDSMN1; SMN2GCKRXRA
	SCHEMBL2644143	0.82	MAOB (0.43)	ALDH1A1HPGDGCKRXRAKCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.