Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.97 |
| ▸ | HPGD | P15428 | 3/20 | 0.97 |
| ▸ | MAPT | P10636 | 2/20 | 0.97 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.67 |
| ▸ | RAB9A | P51151 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.67 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | TSHR | P16473 | 2/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2644495 | 0.80 | ALDH1A1 (0.63) | ALDH1A1HPGDMAPTSMN1; SMN2RAB9A | |
| SCHEMBL2644704 | 0.78 | ALDH1A1 (0.65) | ALDH1A1HPGDMAPTSMN1; SMN2RAB9A | |
| SCHEMBL2644158 | 0.75 | ALDH1A1 (0.61) | ALDH1A1HPGDMAPTSMN1; SMN2RAB9A | |
| SCHEMBL11858187 | 0.73 | SMN1; SMN2 (0.64) | ALDH1A1HPGDMAPTSMN1; SMN2RAB9A | |
| SCHEMBL2655830 | 0.73 | ALDH1A1 (0.70) | ALDH1A1HPGDMAPTSMN1; SMN2RAB9A | |
| SCHEMBL13392950 | 0.72 | ALDH1A1 (0.57) | ALDH1A1HPGDMAPTSMN1; SMN2RAB9A | |
| SCHEMBL2661958 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HPGDMAPTSMN1; SMN2RAB9A | |
| SCHEMBL2653131 | 0.70 | ALDH1A1 (0.66) | ALDH1A1HPGDMAPTSMN1; SMN2RAB9A | |
| SCHEMBL2653601 | 0.70 | ALDH1A1 (0.66) | ALDH1A1HPGDMAPTSMN1; SMN2RAB9A | |
| SCHEMBL2648282 | 0.70 | ALDH1A1 (0.68) | ALDH1A1HPGDMAPTSMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040097557-A1 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | DUFFY JOSEPH L (US) | 2004-05-20 | — | — | US | claimed |
| US-20040097557-A1 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | DUFFY JOSEPH L (US) | 2004-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040097557-A1 | Cyanothiophene derivatives, compositions containing such compounds and methods of use | GLP1R, GPR119, GCGR | ALDH1A1 2652/4885HPGD 1674/4885MAPT 3828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.