Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17052733 | 0.89 | PTGS2 (0.50) | PTGS2POLBHSD17B10RAB9AALDH1A1 | |
| SCHEMBL17045909 | 0.89 | HSD17B10 (0.65) | PTGS2POLBHSD17B10RAB9AALDH1A1 | |
| SCHEMBL17052736 | 0.86 | HSD17B10 (0.48) | PTGS2POLBHSD17B10ALDH1A1GAA | |
| SCHEMBL6232251 | 0.85 | CYP1A2 (0.65) | PTGS2POLBCYP1A2RAB9ANPC1 | |
| SCHEMBL6234337 | 0.85 | CYP1A2 (0.65) | PTGS2POLBCYP1A2RAB9ANPC1 | |
| SCHEMBL6232914 | 0.85 | CYP1A2 (0.65) | PTGS2POLBCYP1A2RAB9ANPC1 | |
| SCHEMBL6234990 | 0.85 | CYP1A2 (0.65) | PTGS2POLBCYP1A2RAB9ANPC1 | |
| SCHEMBL26445663 | 0.84 | CYP1A2 (0.60) | PTGS2POLBHSD17B10CYP1A2RAB9A | |
| SCHEMBL6232508 | 0.83 | CYP1A2 (0.67) | POLBCYP1A2RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL17045927 | 0.83 | EPHX2 (0.52) | PTGS2POLBHSD17B10RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069994-A1 | IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-04-27 | — | — | WO | disclosed |