Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407465 | 0.83 | GRIN1 (0.61) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| SCHEMBL26451008 | 0.82 | SLC6A4 (0.40) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| SCHEMBL23596011 | 0.77 | GRIN1 (0.48) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| SCHEMBL23579031 | 0.77 | GRIN1 (0.48) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| SCHEMBL23579017 | 0.77 | GRIN1 (0.48) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| SCHEMBL28605874 | 0.75 | SMN1; SMN2 (0.44) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| [11C]Ketamine SCHEMBL23579509 | 0.74 | GRIN1 (0.62) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| [11C]Ketamine SCHEMBL8154269 | 0.74 | GRIN1 (0.62) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| [11C]Ketamine SCHEMBL23579178 | 0.74 | GRIN1 (0.62) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D | |
| [11C]Ketamine SCHEMBL8154919 | 0.72 | GRIN1 (0.60) | SLC6A4GRIN1GRIN2AOPRK1GRIN2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230139975-A1 | Arylcyclohexylamine derivatives and process for preparing same | Technische Hochschule Köln (DE) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230139975-A1 | Arylcyclohexylamine derivatives and process for preparing same | DDC, AADAT, SNCA | SLC6A4 538/4885GRIN1 166/4885GRIN2A 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.