Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.37 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.37 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.34 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18561533 | 1.00 | GAA (0.39) | GAAALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL15908419 | 1.00 | GAA (0.39) | GAAALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL14929034 | 1.00 | GAA (0.39) | GAAALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL15241392 | 0.90 | LGALS9 (0.44) | GAAALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL16647467 | 0.90 | LGALS9 (0.44) | GAAALDH1A1LGALS9LGALS1LGALS3 | |
| SCHEMBL14571165 | 0.88 | ALDH1A1 (0.49) | GAAALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL882168 | 0.88 | ALDH1A1 (0.49) | GAAALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL21418908 | 0.88 | ALDH1A1 (0.49) | GAAALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL21418911 | 0.88 | ALDH1A1 (0.49) | GAAALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL14853799 | 0.88 | ALDH1A1 (0.49) | GAAALDH1A1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8133870-B2 | Therapeutic furopyrimidines and thienopyrimidines | BIOCRYST PHARMACEUTICALS, INC. (US) | 2012-03-13 | — | — | US | disclosed |