Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY4R | P50391 | 16/20 | 0.58 |
| ▸ | NPY1R | P25929 | 9/20 | 0.58 |
| ▸ | NPY5R | Q15761 | 8/20 | 0.58 |
| ▸ | TFPI | P10646 | 1/20 | 0.56 |
| ▸ | NPY2R | P49146 | 5/20 | 0.54 |
| ▸ | KISS1R | Q969F8 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26454272 | 0.95 | NPY4R (0.61) | NPY4RNPY1RNPY5RTFPINPY2R | |
| SCHEMBL21581725 | 0.91 | NPY4R (0.62) | NPY4RNPY1RNPY5RTFPINPY2R | |
| SCHEMBL21581728 | 0.87 | TFPI (0.61) | NPY4RNPY1RNPY5RTFPINPY2R | |
| SCHEMBL26454247 | 0.87 | NPY4R (0.57) | NPY4RNPY1RNPY5RTFPINPY2R | |
| SCHEMBL21581732 | 0.86 | NPY4R (0.66) | NPY4RNPY1RNPY5RTFPINPY2R | |
| SCHEMBL21581724 | 0.82 | NPY4R (0.61) | NPY4RNPY1RNPY5RTFPINPY2R | |
| SCHEMBL26455101 | 0.82 | TFPI (0.55) | NPY4RNPY1RNPY5RTFPINPY2R | |
| SCHEMBL26454205 | 0.81 | NPY4R (0.59) | NPY4RNPY1RNPY5RTFPINPY2R | |
| SCHEMBL21581729 | 0.80 | NPY4R (0.46) | NPY4RNPY1RNPY5RTFPINPY2R | |
| SCHEMBL14089458 | 0.79 | NPY4R (0.66) | NPY4RNPY1RNPY5RTFPINPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230133885-A1 | NEW SYNTHETIC METHODS USING NATIVE CHEMICAL LIGATION IN FLOW | THE UNIVERSITY OF SYDNEY (AU) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230133885-A1 | NEW SYNTHETIC METHODS USING NATIVE CHEMICAL LIGATION IN FLOW | SCLY, SRM, SELENOI | NPY4R 3180/4885NPY1R 3765/4885NPY5R 2536/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.