SCHEMBL2645481

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL642347	0.85	GCK (0.44)	GCKKCNH2PTGS2SLC6A4
	SCHEMBL644656	0.79	GCK (0.49)	GCKKCNH2PTGS2HAO1SLC6A4
	SCHEMBL9902848	0.79	GCK (0.49)	GCKKCNH2PTGS2HAO1POLB
	SCHEMBL2644319	0.79	POLB (0.40)	GCKPTGS2HAO1POLBCTDSP1
	SCHEMBL12096277	0.78	GCK (0.48)	GCKKCNH2PTGS2HAO1POLB
	SCHEMBL2644611	0.78	GCK (0.54)	GCKKCNH2
	SCHEMBL643430	0.78	GCK (0.62)	GCKKCNH2
	SCHEMBL9903102	0.78	GCK (0.48)	GCKKCNH2PTGS2HAO1SLC6A4
	SCHEMBL643936	0.78	GCK (0.48)	GCKKCNH2PTGS2HAO1SLC6A4
	SCHEMBL18585491	0.76	CA12 (0.51)	PTGS2TTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.