SCHEMBL26455293

SCHEMBL26455293

C[C@@H]1C[C@@H](C)[C@H]2OC(n3cnc4c(NC(=O)c5ccccc5)ncnc43)C[C@H]21

nearest known ligand 0.53

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ADORA3 P0DMS8 1/20 0.45
P2RY12 Q9H244 8/20 0.43
PRMT6 Q96LA8 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26455308 1.00 ADORA3 (0.45) ADORA3P2RY12PRMT6
SCHEMBL26455122 1.00 ADORA3 (0.45) ADORA3P2RY12PRMT6
SCHEMBL26455444 0.94 ADORA3 (0.48) ADORA3P2RY12PRMT6
SCHEMBL26455313 0.94 ADORA3 (0.48) ADORA3P2RY12PRMT6
SCHEMBL26455086 0.93 ADORA3 (0.48) ADORA3P2RY12
SCHEMBL26455432 0.93 ADORA3 (0.48) ADORA3P2RY12
SCHEMBL20792252 0.84 ADORA3 (0.44) ADORA3P2RY12PRMT6
SCHEMBL26189640 0.83 ADORA1 (0.48)
SCHEMBL18464705 0.83 ADORA1 (0.48)
SCHEMBL21560779 0.83 PRMT6 (0.48) ADORA3P2RY12PRMT6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132377-A9 OLIGONUCLEOTIDES CONJUGATES COMPRISING 7'-5'-ALPHA-ANOMERIC-BICYCLIC SUGAR NUCLEOSIDES ALPHA ANOMERIC SAS (FR) 2023-04-27 US disclosed