SCHEMBL26455409

SCHEMBL26455409

O=C(O)c1cc(OSC(F)(F)C(F)(F)C(F)(F)S(=O)(=O)O)cc(OSC(F)(F)C(F)(F)C(F)(F)S(=O)(=O)O)c1

nearest known ligand 0.36

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LCK P06239 1/20 0.35
FYN P06241 1/20 0.35
WDR5 P61964 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
PLA2G2A P14555 1/20 0.32
AURKA O14965 1/20 0.31
TPX2 Q9ULW0 1/20 0.31
PTPN1 P18031 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26452068 0.93 WDR5 (0.33) LCKFYNWDR5PLA2G2A
SCHEMBL25523388 0.79 LCK (0.37) LCKFYNWDR5MEN1KMT2A
SCHEMBL25916521 0.74
SCHEMBL26042550 0.73 SERPINE1 (0.34)
SCHEMBL25467891 0.73 WDR5 (0.34) LCKFYNWDR5MEN1KMT2A
SCHEMBL16519330 0.72 KMT2A (0.38) LCKFYNWDR5MEN1KMT2A
SCHEMBL9966114 0.67 KMT2A (0.43) MEN1KMT2A
SCHEMBL7176115 0.66 CA12 (0.41) LCKFYNMEN1KMT2APLA2G2A
SCHEMBL13882859 0.66 LCK (0.33) LCKFYN
SCHEMBL12762006 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230133710-A1 ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, RESIST FILM, PATTERN FORMING METHOD, AND METHOD FOR MANUFACTURING ELECTRONIC DEVICE FUJIFILM CORPORATION (JP) 2023-05-04 US disclosed