⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Isophthalic Dicarboxaldehyde SCHEMBL180566 | 0.83 | ALDH1A1 (0.67) | — | |
| Isophthalic Dicarboxaldehyde SCHEMBL4952540 | 0.83 | ALDH1A1 (0.67) | — | |
| Isophthalic Dicarboxaldehyde SCHEMBL28611144 | 0.80 | ALDH1A1 (0.67) | — | |
| Isophthalic Dicarboxaldehyde SCHEMBL4304012 | 0.78 | ALDH1A1 (0.63) | — | |
| Isophthalic Dicarboxaldehyde SCHEMBL20477528 | 0.78 | ALDH1A1 (0.61) | — | |
| SCHEMBL5544682 | 0.77 | — | — | |
| Isophthalic Dicarboxaldehyde SCHEMBL16267528 | 0.76 | ALDH1A1 (0.58) | — | |
| SCHEMBL346974 | 0.76 | TRIM24 (0.64) | — | |
| SCHEMBL27621710 | 0.74 | TRIM24 (0.68) | — | |
| SCHEMBL713815 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103249305-A | Method for treating ophthalmic diseases using kinase inhibitor compounds in prodrug forms | INSPIRE PHARMACEUTICALS INC | 2013-08-14 | — | — | CN | disclosed |
| EP-1702919-B1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | MSD KK (JP) | 2012-05-30 | — | — | EP | disclosed |
| CN-102442941-A | Polycyclic acid compounds useful as crth2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2012-05-09 | — | — | CN | disclosed |
| CN-101175724-B | pyrrolidine derivative or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-12-07 | — | — | CN | disclosed |
| US-7728025-B2 | 2-heteroaryl-substituted benzimidazole derivative | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2010-06-01 | — | — | US | disclosed |
| CN-101636386-A | Polycyclic acid compounds useful as CRTH2 antagonists and antiallergic agents | ASTELLAS PHARMA INC | 2010-01-27 | — | — | CN | disclosed |
| CN-101175724-A | Pyrrolidine derivative or salt thereof | ASTELLAS PHARMA INC (JP) | 2008-05-07 | — | — | CN | disclosed |
| CN-100383138-C | N-monoacetyl o-phenylenediamines, their fused heterocyclic derivatives and their use as medicaments | HOFFMANN LA ROCHE (CH) | 2008-04-23 | — | — | CN | disclosed |
| US-20080070928-A1 | Novel 2-Heteroaryl-Substituted Benzimidazole Derivative | MSD K.K. (JP) | 2008-03-20 | — | — | US | disclosed |
| EP-1702919-A1 | NOVEL 2-HETEROARYL-SUBSTITUTED BENZIMIDAZOLE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |
| CN-1747948-A | Novel n-monoacylated o-phenylenediamines, their condensed heterocyclic derivatives and their use as pharmaceutical agents | HOFFMANN LA ROCHE (CH) | 2006-03-15 | — | — | CN | disclosed |
| EP-1585517-A1 | USE OF SUBSTITUTED 2-PHENYLBENZIMIDAZOLES AS MEDICAMENTS | Boehringer Ingelheim International GmbH (DE) | 2005-10-19 | — | — | EP | disclosed |
| WO-2004062663-A1 | USE OF SUBSTITUTED 2-PHENYLBENZIMIDAZOLES AS MEDICAMENTS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2004-07-29 | — | — | WO | disclosed |
| US-6627714-B2 | Copolymerizing ethylene and dicyclopentadiene or tricyclopentadiene, and cyclic olefin in presence of metallocene catalyst to produce copolymer | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2003-09-30 | — | — | US | disclosed |
| US-20020058767-A1 | Method for producing an olefin type copolymer having a cyclic structure | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2002-05-16 | — | — | US | disclosed |
| EP-1205497-A2 | Method for producing an olefin type copolymer having a cyclic structure | MARUZEN PETROCHEMICAL CO., LTD. (JP) | 2002-05-15 | — | — | EP | disclosed |
| CN-1282340-A | Solid catalysts for polymerization of olefins and process for production of olefin polymers therewith | MARUZEN PETROCHEM CO LTD (JP) | 2001-01-31 | — | — | CN | disclosed |
| EP-0808319-A1 | EPIPODOPHYLLOTOXIN TRIARYLOXYACETYL DERIVATIVES, METHOD FOR PREPARING SAME, AND USE OF SAID DERIVATIVES AS CANCER DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1997-11-26 | — | — | EP | disclosed |
| WO-1996024602-A1 | EPIPODOPHYLLOTOXIN TRIARYLOXYACETYL DERIVATIVES, METHOD FOR PREPARING SAME, AND USE OF SAID DERIVATIVES AS CANCER DRUGS | PIERRE FABRE MEDICAMENT (FR) | 1996-08-15 | — | — | WO | disclosed |