Isophthalic Dicarboxaldehyde

Isophthalic Dicarboxaldehyde

SCHEMBL4304012

O=Cc1ccc(C=O)cc1.O=Cc1cccc(C=O)c1

nearest known ligand 0.63

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.63
CYP2A6 P11509 4/20 0.63
UNG P13051 1/20 0.54
KDM4E B2RXH2 2/20 0.50
PTGS2 P35354 1/20 0.50
RAB9A P51151 1/20 0.50
HSD17B10 Q99714 1/20 0.50
ALDH5A1 P51649 1/20 0.50
ABAT P80404 1/20 0.50
SRC P12931 1/20 0.47
TRIM24 O15164 1/20 0.45
TRIM33 Q9UPN9 1/20 0.45
TSHR P16473 1/20 0.44
TYR P14679 1/20 0.44
CYP2A13 Q16696 1/20 0.44
MAOA P21397 1/20 0.44
MAOB P27338 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Isophthalic Dicarboxaldehyde SCHEMBL4952540 0.94 ALDH1A1 (0.67) ALDH1A1CYP2A6UNGKDM4EPTGS2
Isophthalic Dicarboxaldehyde SCHEMBL180566 0.94 ALDH1A1 (0.67) ALDH1A1CYP2A6UNGKDM4EPTGS2
Isophthalic Dicarboxaldehyde SCHEMBL28611144 0.91 ALDH1A1 (0.67) ALDH1A1CYP2A6UNGKDM4EPTGS2
Isophthalic Dicarboxaldehyde SCHEMBL20477528 0.88 ALDH1A1 (0.61) ALDH1A1CYP2A6UNGKDM4EPTGS2
Isophthalic Dicarboxaldehyde SCHEMBL16267528 0.86 ALDH1A1 (0.58) ALDH1A1CYP2A6UNGKDM4EPTGS2
SCHEMBL29700451 0.83 TRIM24 (0.67) ALDH1A1CYP2A6UNGKDM4EPTGS2
SCHEMBL5916092 0.83 TRIM24 (0.67) ALDH1A1CYP2A6UNGKDM4EPTGS2
Benzaldehyde SCHEMBL16279843 0.81 ALDH1A1 (0.93) ALDH1A1CYP2A6UNGKDM4EHSD17B10
Benzaldehyde SCHEMBL29133494 0.81
Isophthalic Dicarboxaldehyde SCHEMBL9568121 0.81 ALDH1A1 (0.60) ALDH1A1CYP2A6UNGKDM4EPTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3352998-B1 USE OF AN ESTERIFIED AROMATIC POLYPHENOL DERIVATIVE FOR THE PRODUCTION OF A PHENOL-ALDEHYDE RESIN FOR REINFORCEMENT OF A RUBBER COMPOSITION MICHELIN & CIE (FR) 2020-06-10 EP claimed
WO-2009100879-A2 BROAD SPECTRUM DISINFECTING AND STERILIZING COMPOSITION LONZA INC. (US) 2009-08-20 WO disclosed