SCHEMBL26460808

SCHEMBL26460808

c1ccc(-c2nc(-c3ccccc3)c3cc(-c4ccc5c(-c6ccccc6)c6cccc7c6c(c5c4)-c4ccccc4-c4ccccc4-7)ccc3n2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
WHR1 P49842 1/20 0.44
MEN1 O00255 2/20 0.44
KMT2A Q03164 2/20 0.44
ATM Q13315 1/20 0.44
PIK3CD O00329 1/20 0.36
PIK3CA P42336 1/20 0.36
PIK3CB P42338 1/20 0.36
MTOR P42345 1/20 0.36
PIK3CG P48736 1/20 0.36
PDK1 Q15118 1/20 0.34
HPGD P15428 1/20 0.33
MAPT P10636 4/20 0.33
LMNA P02545 2/20 0.33
ESR1 P03372 2/20 0.33
ESR2 Q92731 2/20 0.33
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
ABCG2 Q9UNQ0 7/20 0.32
NT5E P21589 1/20 0.32
SMN1; SMN2 Q16637 3/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26460811 0.92 MEN1 (0.48) WHR1MEN1KMT2AATMPDK1
SCHEMBL26461379 0.82 ENPP1 (0.40) MEN1KMT2AATMHPGDMAPT
SCHEMBL26464050 0.81 MEN1 (0.46) WHR1MEN1KMT2AATMPDK1
SCHEMBL26461377 0.80 MEN1 (0.47) MEN1KMT2AHPGDMAPTLMNA
SCHEMBL26460809 0.79 LMNA (0.47) MEN1KMT2ALMNAESR1ESR2
SCHEMBL22139309 0.78 MEN1 (0.60) WHR1MEN1KMT2AATMPDK1
SCHEMBL21667432 0.78 MEN1 (0.59) WHR1MEN1KMT2AATMPIK3CD
SCHEMBL19009597 0.78 MEN1 (0.54) WHR1MEN1KMT2AATMPDK1
SCHEMBL26461034 0.78 ALDH1A1 (0.44) MEN1KMT2AATMPIK3CAHPGD
SCHEMBL22139312 0.77 MEN1 (0.59) WHR1MEN1KMT2AATMPDK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023065996-A1 ANTHRACENE DERIVATIVE, ORGANIC ELECTROLUMINESCENT MATERIAL, LIGHT-EMITTING DEVICE, AND CONSUMER PRODUCT 上海八亿时空先进材料有限公司 2023-04-27 WO disclosed