Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | PAM | P19021 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 4/20 | 0.48 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL873430 | 0.85 | TSHR (1.00) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL28134676 | 0.83 | TSHR (0.76) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL27120274 | 0.83 | TSHR (0.76) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL27883126 | 0.83 | TSHR (0.96) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| Hydrochloric Acid SCHEMBL27332250 | 0.83 | TSHR (0.96) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL5761203 | 0.81 | TSHR (0.73) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL5599202 | 0.81 | TSHR (0.73) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL12412855 | 0.81 | TSHR (0.73) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL12412853 | 0.81 | TSHR (0.73) | TSHRALDH1A1MAPK1L3MBTL1PAM | |
| SCHEMBL27484257 | 0.81 | TSHR (0.93) | TSHRALDH1A1MAPK1L3MBTL1PAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230137816-A1 | ADMINISTRATION OF CALCIUM CHANNEL TRPC6 INHIBITORS USING BALLOONS, STENTS OR OTHER MEDICAL DEVICES | DEUTSCHES HERZZENTRUM MUENCHEN DES FREISTAATES BAYERN (DE) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230137816-A1 | ADMINISTRATION OF CALCIUM CHANNEL TRPC6 INHIBITORS USING BALLOONS, STENTS OR OTHER MEDICAL DEVICES | TRPC6, TRPC1, ORAI1 | TSHR 3703/4885ALDH1A1 4066/4885MAPK1 648/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.