Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terbutaline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 4/20 | 0.84 |
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | CASP7 | P55210 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | CASP1 | P29466 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.84 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terbutaline SCHEMBL5178614 | 1.00 | LMNA (1.00) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL41870 | 1.00 | LMNA (1.00) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL3937997 | 1.00 | LMNA (1.00) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL9614480 | 1.00 | LMNA (1.00) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL2836997 | 0.98 | LMNA (0.97) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL8030115 | 0.98 | LMNA (0.97) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL11220263 | 0.98 | LMNA (0.97) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL9524623 | 0.98 | LMNA (0.97) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL10783388 | 0.98 | LMNA (0.97) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL11332074 | 0.97 | LMNA (0.94) | LMNAKMT2AHIF1ACASP7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 11064 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260076872-A1 | POLYMER VIALS WITH SUBSTANTIALLY FLAT BOTTOMS AND INJECTION STRETCH BLOW MOLDING METHODS FOR MAKING THE SAME | SIO2 MEDICAL PRODUCTS LLC (US) | 2026-03-19 | — | — | US | claimed |
| US-20250242092-A1 | SiOx BARRIER FOR PHARMACEUTICAL PACKAGE AND COATING PROCESS | SIO2 MEDICAL PRODUCTS INC (US) | 2025-07-31 | — | — | US | claimed |
| CN-120114422-A | Atomized inhalation solution for treating bronchial asthma and preparation method and application thereof | 中南大学湘雅二医院 | 2025-06-10 | — | — | CN | claimed |
| CN-120078752-A | Particles for large-dose water-soluble medicine inhalation powder aerosol and preparation method thereof | 沈阳药科大学 | 2025-06-03 | — | — | CN | claimed |
| CN-119632957-B | Terbutaline sulfate solution for aerosol inhalation and preparation method thereof | 江苏长泰药业股份有限公司 | 2025-05-27 | — | — | CN | claimed |
| EP-4547220-A1 | A STABLE ORAL LIQUID COMPOSITION COMPRISING TERBUTALINE & GUAIFENESIN | Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi (TR) | 2025-05-07 | — | — | EP | claimed |
| US-12257371-B2 | SiOx barrier for pharmaceutical package and coating process | SIO2 MEDICAL PRODUCTS, LLC (US) | 2025-03-25 | — | — | US | claimed |
| CN-119632957-A | Terbutaline sulfate solution for aerosol inhalation and preparation method thereof | 江苏长泰药业股份有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119607064-A | Application of pharmaceutical composition in prevention and treatment of pulmonary diseases | 上海黄海制药有限责任公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119455432-A | Continuous microfluidization crystallizer and preparation method of pharmaceutical active ingredient micro-nano particles | 奥锐特药业股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| US-4305870-A | Intravenous plasma derivatives and their production | IMMUNO AKTIENGESELLSCHAFT FUR CHEMISCH-MEDIZINISCHE PRODUKTE (AT) | 1981-12-15 | — | — | US | claimed |
| US-4193861-A | PRESSURIZATION, IMMERSION IN ELECTROLYTE | BASF WYANDOTTE CORPORATION (US) | 1980-03-18 | — | — | US | claimed |
| US-4123728-A | Electrogenerated chemiluminescent (ECL) laser | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY (US) | 1978-10-31 | — | — | US | claimed |
| US-4120807-A | Process for producing hexagonal-system ferrite powder | DOWA MINING CO., LTD. (JP) | 1978-10-17 | — | — | US | claimed |
| US-4063880-A | ANIONIC AND NONIONIC | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-12-20 | — | — | US | claimed |
| US-4042677-A | STANNOUS TARTRATE, HUMAN SERUM ALBUMIN | UNION CARBIDE CORPORATION (US) | 1977-08-16 | — | — | US | claimed |
| US-4038301-A | REMOVAL AND RECOVERY OF ORGANOLEAD COMPOUNDS FROM ACTIVATED CARBON AND RECOVERY OF THE ACTIVATED CARBON | PPG INDUSTRIES, INC. (US) | 1977-07-26 | — | — | US | claimed |
| US-4017647-A | Method for providing enteric coatings on solid dosage forms | SHIN-ETSU CHEMICAL COMPANY LIMITED (JA) | 1977-04-12 | — | — | US | claimed |
| US-3997525-A | Tetra-125 iodo-di-tyramine of digitalis derivative and process for making the same | BIO-TEC, INC. (US) | 1976-12-14 | — | — | US | claimed |
| US-3946077-A | CATALYTIC OXIDATION TO FORM ALCOHOLS AND KETONES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-03-23 | — | — | US | claimed |