Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Terbutaline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 known ✓ | P07550 | 4/20 | 0.84 |
| ▸ | LMNA | P02545 | 6/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 3/20 | 1.00 |
| ▸ | HIF1A | Q16665 | 3/20 | 1.00 |
| ▸ | CASP7 | P55210 | 2/20 | 1.00 |
| ▸ | MEN1 | O00255 | 2/20 | 1.00 |
| ▸ | BLM | P54132 | 2/20 | 1.00 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 1.00 |
| ▸ | CASP1 | P29466 | 1/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 1.00 |
| ▸ | TSHR | P16473 | 3/20 | 0.84 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.84 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.84 |
| ▸ | APEX1 | P27695 | 1/20 | 0.65 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.53 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terbutaline SCHEMBL5178614 | 1.00 | LMNA (1.00) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL3937997 | 1.00 | LMNA (1.00) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL26462 | 1.00 | LMNA (1.00) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL9614480 | 1.00 | LMNA (1.00) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL2836997 | 0.98 | LMNA (0.97) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL8030115 | 0.98 | LMNA (0.97) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL11220263 | 0.98 | LMNA (0.97) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL9524623 | 0.98 | LMNA (0.97) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL10783388 | 0.98 | LMNA (0.97) | LMNAKMT2AHIF1ACASP7MEN1 | |
| Terbutaline SCHEMBL11332074 | 0.97 | LMNA (0.94) | LMNAKMT2AHIF1ACASP7MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 8097 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120114422-A | Atomized inhalation solution for treating bronchial asthma and preparation method and application thereof | 中南大学湘雅二医院 | 2025-06-10 | — | — | CN | claimed |
| CN-120078752-A | Particles for large-dose water-soluble medicine inhalation powder aerosol and preparation method thereof | 沈阳药科大学 | 2025-06-03 | — | — | CN | claimed |
| CN-119632957-B | Terbutaline sulfate solution for aerosol inhalation and preparation method thereof | 江苏长泰药业股份有限公司 | 2025-05-27 | — | — | CN | claimed |
| EP-4547220-A1 | A STABLE ORAL LIQUID COMPOSITION COMPRISING TERBUTALINE & GUAIFENESIN | Abdi Ibrahim Ilac Sanayi ve Ticaret Anonim Sirketi (TR) | 2025-05-07 | — | — | EP | claimed |
| CN-119632957-A | Terbutaline sulfate solution for aerosol inhalation and preparation method thereof | 江苏长泰药业股份有限公司 | 2025-03-18 | — | — | CN | claimed |
| CN-119607064-A | Application of pharmaceutical composition in prevention and treatment of pulmonary diseases | 上海黄海制药有限责任公司 | 2025-03-14 | — | — | CN | claimed |
| CN-119455432-A | Continuous microfluidization crystallizer and preparation method of pharmaceutical active ingredient micro-nano particles | 奥锐特药业股份有限公司 | 2025-02-18 | — | — | CN | claimed |
| CN-118236359-B | Application of terbutaline sulfate in preventing and treating intestinal ischemia reperfusion injury | 南方医科大学南方医院 | 2025-01-21 | — | — | CN | claimed |
| CN-119318646-A | Terbutaline sulfate aerosol inhalation solution and preparation method thereof | 南京力成药业有限公司 | 2025-01-17 | — | — | CN | claimed |
| CN-118845724-A | Terbutaline sulfate and budesonide inhalation suspension and preparation method thereof | 亿药通(河北)生物科技有限公司 | 2024-10-29 | — | — | CN | claimed |
| US-4895719-A | SUSPENSION, ENCAPSULATION, DRUG DELIVERY | LIPOSOME TECHNOLOGY, INC. (US) | 1990-01-23 | — | — | US | claimed |
| EP-0298984-A1 | COMPOSITIONS OF LIPOSOMES AND $g(b) 2?-RECEPTOR ACTIVE SUBSTANCES | Aktiebolaget Draco (SE) | 1989-01-18 | — | — | EP | claimed |
| EP-0282537-A1 | A NEW SYSTEM FOR ADMINISTRATION OF LIPOSOMES TO MAMMALS | Aktiebolaget Draco (SE) | 1988-09-21 | — | — | EP | claimed |
| WO-1988001862-A1 | A NEW SYSTEM FOR ADMINISTRATION OF LIPOSOMES TO MAMMALS | AKTIEBOLAGET DRACO (SE) | 1988-03-24 | — | — | WO | claimed |
| EP-0260241-A1 | A new system for administration of liposomes to mammals | Aktiebolaget Draco (SE) | 1988-03-16 | — | — | EP | claimed |
| WO-1987005803-A1 | COMPOSITIONS OF LIPOSOMES AND beta2-RECEPTOR ACTIVE SUBSTANCES | AKTIEBOLAGET DRACO (SE) | 1987-10-08 | — | — | WO | claimed |
| EP-0189861-A2 | Percutaneous absorption accelerator for ionic water-soluble medicine | SHOWA DENKO KABUSHIKI KAISHA (JP) | 1986-08-06 | — | — | EP | claimed |
| US-4472436-A | HIGH DENSITY LIPOOROTEIN, TERBUTALINE | NEO-BIONICS, INC. (US) | 1984-09-18 | — | — | US | claimed |
| US-4409237-A | ASTHMA | FISONS LIMITED (GB) | 1983-10-11 | — | — | US | claimed |
| US-4369172-A | Prolonged release therapeutic compositions based on hydroxypropylmethylcellulose | FOREST LABORATORIES INC. (US) | 1983-01-18 | — | — | US | claimed |