Para-Methoxyamphetamine

Para-Methoxyamphetamine

SCHEMBL264634

COc1ccc(CC(C)N)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 1.00
CYP1A2 P05177 1/20 0.66
CYP2D6 P10635 1/20 0.66
CYP2C19 P33261 1/20 0.66
TAAR1 Q96RJ0 4/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Para-Methoxyamphetamine SCHEMBL895775 1.00 SLC6A4 (1.00) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
Para-Methoxyamphetamine SCHEMBL394418 1.00 SLC6A4 (1.00) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
Para-Methoxyamphetamine SCHEMBL7253563 0.98 SLC6A4 (0.96) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
Para-Methoxyamphetamine SCHEMBL10975159 0.98 SLC6A4 (0.96) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
SCHEMBL9468376 0.94 SLC6A4 (0.89) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
SCHEMBL9468512 0.94 SLC6A4 (0.89) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
SCHEMBL6540600 0.86 SLC6A4 (0.74) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
SCHEMBL7528408 0.84 SLC6A4 (0.73) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
SCHEMBL656814 0.84 SLC6A4 (0.73) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
SCHEMBL10774940 0.84 SLC6A4 (0.73) SLC6A4TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1012 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4633638-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) Luminous Mind Inc. (US) 2025-10-22 EP claimed
EP-4618980-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES Freedom Biosciences, Inc. (US) 2025-09-24 EP claimed
US-20250213647-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA 2025-07-03 US claimed
US-20250130211-A1 METHOD OF SCREENING NEW PSYCHOACTIVE SUBSTANCE AND PLATFORM THEREOF NATIONAL TAIWAN UNIVERSITY (TW) 2025-04-24 US claimed
WO-2024130044-A1 TREATMENT OF PSYCHOLOGICAL FACTORS AFFECTING OTHER MEDICAL CONDITIONS (PFAOMC) LUMINOUS MIND INC. (US) 2024-06-20 WO claimed
WO-2024107445-A1 ENHANCEMENT OF THE EFFICACY OF SEROTONERGIC PSYCHEDELIC DRUGS IN THE TREATMENT OR PREVENTION OF CERTAIN NEUROPSYCHIATRIC DISORDERS THROUGH INHIBITION OF TYPE-9 PHOSPHODIESTERASES FREEDOM BIOSCIENCES, INC. (US) 2024-05-23 WO claimed
CN-117904097-A Self-assembled protein scaffold co-immobilized enzyme and application thereof 浙江工业大学 2024-04-19 CN claimed
WO-2023192319-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA (US) 2023-10-05 WO claimed
CN-115656376-A Method for separating and detecting formoterol related substances 苏州易合医药有限公司 2023-01-31 CN claimed
EP-4061359-A1 TRYPTAMINE COMPOSITIONS FOR ENHANCING NEURITE OUTGROWTH Turtle Bear Holdings, LLC (US) 2022-09-28 EP claimed
EP-1704140-A1 SYNTHESIS OF OPTICALLY PURE (R)-5-(2-AMINOPROPYL)-2-METHOXYBENZENESULPHONAMIDE LEK Pharmaceuticals D.D. (SI) 2006-09-27 EP claimed
US-20060148046-A1 Enzymatic process for the preparation of an intermediate compound and use thereof for the synthesis of tamsulosin hydrochloride QUIMICA SINTETICA, S.A. 2006-07-06 US claimed
WO-2006070285-A2 ENZYMATIC PREPARATION OF AN INTERMEDIATE COMPOUND FOR THE SYNTHESIS OF TAMSULOSIN QUIMICA SINTETICA, S.A. (ES) 2006-07-06 WO claimed
WO-2005063701-A1 SYNTHESIS OF OPTICALLY PURE (R)-5-(2-AMINOPROPYL)-2-METHOXYBENZENESULPHONAMIDE LEK PHARMACEUTICALS D.D. (CH) 2005-07-14 WO claimed
US-20050020659-A1 Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists ELAN PHARMACEUTICALS, INC. 2005-01-27 US claimed
EP-0848065-B1 Method for improving optical purity of an amine compound SUMITOMO CHEMICAL CO (JP) 2003-04-02 EP claimed
US-20020013372-A1 Pharmacophore models for the identification of the CYP2D6 inhibitory potency of selective serotonin reuptake inhibitors PFIZER PRODUCTS INC. 2002-01-31 US claimed
EP-1134290-A2 Pharmacophore models for the identification of the CYP2D6 inhibitory potency of selective serotonin reuptake inhibitors Pfizer Products Inc. (US) 2001-09-19 EP claimed
US-5965432-A PREFERENTIALLY METABOLIZING (S) ENANTOMORPH OF MIXTURE USING CULTURE OF ARTHROBACTER, CULTURE LIQUID, GEL IMMOBILIZED CELLS, FREEZE-DRIED OR ACETONE-DRIED CELLS, GROUND OR AUTODIGESTED CELLS, ULTRASONIC TREATED OR EXTRACTED CELLS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-10-12 US claimed
EP-0848065-A2 Method for improving optical purity of an amine compound SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1998-06-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050020659-A1 Substituted pyrazole derivatives and related compounds as bradykinin B1 receptor antagonists BDKRB1, BDKRB2, BRS3 SLC6A4 2641/4885CYP1A2 1124/4885CYP2D6 1338/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.