Para-Methoxyamphetamine

Para-Methoxyamphetamine

SCHEMBL895775

COc1ccc(C[C@H](C)N)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 1/20 1.00
CYP1A2 P05177 1/20 0.66
CYP2D6 P10635 1/20 0.66
CYP2C19 P33261 1/20 0.66
TAAR1 Q96RJ0 4/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Para-Methoxyamphetamine SCHEMBL394418 1.00 SLC6A4 (1.00) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
Para-Methoxyamphetamine SCHEMBL264634 1.00 SLC6A4 (1.00) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
Para-Methoxyamphetamine SCHEMBL7253563 0.98 SLC6A4 (0.96) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
Para-Methoxyamphetamine SCHEMBL10975159 0.98 SLC6A4 (0.96) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
SCHEMBL9468376 0.94 SLC6A4 (0.89) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
SCHEMBL9468512 0.94 SLC6A4 (0.89) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
SCHEMBL6540600 0.86 SLC6A4 (0.74) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
SCHEMBL7528408 0.84 SLC6A4 (0.73) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
SCHEMBL656814 0.84 SLC6A4 (0.73) SLC6A4CYP1A2CYP2D6CYP2C19TAAR1
SCHEMBL10774940 0.84 SLC6A4 (0.73) SLC6A4TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 271 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250213647-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA 2025-07-03 US claimed
WO-2023192319-A1 CHEMOKINE RECEPTORS AND ALPHA1 ADRENERGIC RECEPTORS/VASOPRESSIN RECEPTORS 1A HETEROMERS AS DRUG TARGETS FOR DISEASE UNIVERSITY OF SOUTH FLORIDA (US) 2023-10-05 WO claimed
US-20210137854-A1 TAAR Receptor Agonists for the Treatment of Alopecia JUPITER WELLNESS INC. 2021-05-13 US claimed
WO-2020023084-A1 TAAR RECEPTOR AGONISTS FOR THE TREATMENT OF ALOPECIA APPLIED BIOLOGY, INC. (US) 2020-01-30 WO claimed
US-9435816-B2 Deuterium free, stable isotope labeled 2-phenylethylamine hallucinogens and/or stimulants, methods of their preparation and their use CHIRON AS (NO) 2016-09-06 US claimed
WO-2014153099-A2 METHOD FOR USING EXHALED BREATH TO DETERMINE THE PRESENCE OF DRUG Pulmonary Analytics (US) 2014-09-25 WO claimed
US-20140288454-A1 Method For Using Exhaled Breath to Determine the Presence of Drug Pulmonary Analytics (US) 2014-09-25 US claimed
US-20140227792-A1 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE CHIRON A/S (NO) 2014-08-14 US claimed
WO-2013014287-A2 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE CHIRON AS (NO) 2013-01-31 WO claimed
EP-2551675-A1 Deuterium free, stable isotope labeled 2-phenylethylamine hallucinogens and/or stimulants, methods fo their preparation and their use Chiron AS (NO) 2013-01-30 EP claimed
US-20060148046-A1 Enzymatic process for the preparation of an intermediate compound and use thereof for the synthesis of tamsulosin hydrochloride QUIMICA SINTETICA, S.A. 2006-07-06 US claimed
WO-2006070285-A2 ENZYMATIC PREPARATION OF AN INTERMEDIATE COMPOUND FOR THE SYNTHESIS OF TAMSULOSIN QUIMICA SINTETICA, S.A. (ES) 2006-07-06 WO claimed
WO-2026106796-A1 SYSTEM AND METHOD FOR THE TREATMENT OF TELOGEN EFFLUVIUM, ANDROGENETIC ALOPECIA, AND OTHER HAIR LOSS DISORDERS FOLLEA INTERNATIONAL (US) 2026-05-21 WO disclosed
EP-4720030-A1 ASYMMETRIC PHENYLALKYLAMINES Alexander Shulgin Research Institute, Inc. (US) 2026-04-08 EP disclosed
US-20260041652-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA FOLLEA INT (US) 2026-02-12 US disclosed
US-12534428-B2 Non-distillative process for manufacturing high purity amphetamines Pharmapotheca A, Inc. (US) 2026-01-27 US disclosed
US-5508199-A A CLONED CDNA ENCODING DEBRISOQUINE 4-HYDROXYLASE GENE; PROBES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 1996-04-16 US disclosed
EP-0255728-B1 PHENOXYACETIC ACID COMPOUNDS, THEIR PREPARATION, PHARMACEUTICAL COMPOSITION AND USE TANABE SEIYAKU CO., LTD. (JP) 1991-11-27 EP disclosed
US-4866196-A ANTICOAGULANTS TANABE SEIYAKU CO., LTD. (JP) 1989-09-12 US disclosed
EP-0255728-A2 Phenoxyacetic acid compounds, their preparation, pharmaceutical composition and use TANABE SEIYAKU CO., LTD. (JP) 1988-02-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140227792-A1 DEUTERIUM FREE, STABLE ISOTOPE LABELED 2-PHENYLETHYLAMINE HALLUCINOGENS AND/OR STIMULANTS, METHODS OF THEIR PREPARATION AND THEIR USE PNMT, HTR2C, HTR2A SLC6A4 50/4885CYP1A2 59/4885CYP2D6 38/4885
US-12534428-B2 Non-distillative process for manufacturing high purity amphetamines SMS, SRMS, SRM SLC6A4 14/4885CYP1A2 1411/4885CYP2D6 387/4885
US-20260041652-A1 SYSTEM AND METHOD FOR PREVENTING ALOPECIA DYRK4, DYRK2, STRA6 SLC6A4 56/4885CYP1A2 3368/4885CYP2D6 3065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.