Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26465817 | 0.87 | CACNA1H (0.38) | CACNA1HLMNAIDO1SMN1; SMN2 | |
| SCHEMBL26464641 | 0.86 | HTT (0.48) | CACNA1HTSHRKDM4EHPGDKMT2A | |
| SCHEMBL26465688 | 0.85 | HPGD (0.53) | CACNA1HTSHRKDM4EHPGDKMT2A | |
| SCHEMBL26466594 | 0.81 | HPGD (0.49) | CACNA1HTSHRKDM4EHPGDKMT2A | |
| SCHEMBL26466243 | 0.81 | HPGD (0.49) | CACNA1HTSHRKDM4EHPGDKMT2A | |
| SCHEMBL26466250 | 0.81 | HPGD (0.49) | CACNA1HTSHRKDM4EHPGDKMT2A | |
| SCHEMBL26465684 | 0.75 | HPGD (0.54) | CACNA1HTSHRKDM4EHPGDKMT2A | |
| SCHEMBL26465818 | 0.75 | CACNA1H (0.42) | CACNA1HTSHRKDM4EHPGDKMT2A | |
| SCHEMBL26466097 | 0.74 | CACNA1H (0.45) | CACNA1HTSHRKDM4EHPGDKMT2A | |
| SCHEMBL26465813 | 0.74 | MAPT (0.43) | CACNA1HKDM4EHPGDLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |