Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.39 |
| ▸ | UBE2M | P61081 | 1/20 | 0.39 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26465688 | 0.89 | HPGD (0.53) | MAPTTP53CACNA1HLMNAALDH1A1 | |
| SCHEMBL26465818 | 0.88 | CACNA1H (0.42) | MAPTTP53CACNA1HLMNAALDH1A1 | |
| SCHEMBL26465825 | 0.86 | ALDH1A1 (0.44) | MAPTCACNA1HLMNAALDH1A1USP2 | |
| SCHEMBL26465693 | 0.86 | CACNA1H (0.41) | CACNA1HALDH1A1HPGDKDM4EGLA | |
| SCHEMBL26465703 | 0.85 | CACNA1H (0.40) | MAPTCACNA1HLMNAALDH1A1CYP3A4 | |
| SCHEMBL26465810 | 0.85 | CACNA1H (0.47) | MAPTTP53CACNA1HLMNAALDH1A1 | |
| SCHEMBL26465080 | 0.82 | CACNA1H (0.56) | MAPTCACNA1HLMNACYP3A4CYP2D6 | |
| SCHEMBL26466097 | 0.81 | CACNA1H (0.45) | MAPTTP53CACNA1HLMNAALDH1A1 | |
| SCHEMBL26466001 | 0.80 | L3MBTL1 (0.48) | MAPTCACNA1HLMNAALDH1A1USP2 | |
| SCHEMBL26466012 | 0.80 | CACNA1H (0.45) | CACNA1HALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023192669-A1 | T-TYPE CALCIUM CHANNEL MODULATORS COMPRISING A PIPERAZINE OR 1,4-DIAZEPANE CORE AND METHODS OF USE THEREOF | PRAXIS PRECISION MEDICINES, INC. (US) | 2023-10-05 | — | — | WO | disclosed |