Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 17/20 | 0.68 |
| ▸ | ADCYAP1R1 | P41586 | 2/20 | 0.49 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2646472 | 1.00 | GCGR (0.68) | GCGRADCYAP1R1SPHK2SPHK1 | |
| SCHEMBL2653548 | 0.89 | GCGR (0.75) | GCGRSPHK2SPHK1 | |
| SCHEMBL2653547 | 0.89 | GCGR (0.75) | GCGRSPHK2SPHK1 | |
| SCHEMBL7239651 | 0.85 | GCGR (0.80) | GCGRADCYAP1R1 | |
| SCHEMBL7239653 | 0.85 | GCGR (0.80) | GCGRADCYAP1R1 | |
| SCHEMBL9071652 | 0.84 | GCGR (0.55) | GCGR | |
| SCHEMBL2647425 | 0.84 | GCGR (0.73) | GCGR | |
| SCHEMBL2645708 | 0.83 | GCGR (0.68) | GCGRADCYAP1R1 | |
| SCHEMBL2645711 | 0.83 | GCGR (0.68) | GCGRADCYAP1R1 | |
| SCHEMBL2646990 | 0.83 | GCGR (0.80) | GCGRADCYAP1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | claimed |
| EP-1140823-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-10 | — | — | EP | claimed |
| WO-2000039088-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-06 | — | — | WO | claimed |
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-1140823-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039088-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-06 | — | — | WO | disclosed |