Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 16/20 | 0.75 |
| ▸ | SPHK2 | Q9NRA0 | 2/20 | 0.45 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2653547 | 1.00 | GCGR (0.75) | GCGRSPHK2SPHK1ALDH1A1HPGD | |
| SCHEMBL2646472 | 0.89 | GCGR (0.68) | GCGRSPHK2SPHK1 | |
| SCHEMBL2646473 | 0.89 | GCGR (0.68) | GCGRSPHK2SPHK1 | |
| SCHEMBL2647316 | 0.86 | GCGR (1.00) | GCGRALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL2647315 | 0.86 | GCGR (1.00) | GCGRALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL2646991 | 0.84 | GCGR (0.69) | GCGR | |
| SCHEMBL2647970 | 0.82 | GCGR (0.85) | GCGRALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL2646532 | 0.82 | GCGR (0.83) | GCGRALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL2646533 | 0.82 | GCGR (0.83) | GCGRALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL2647968 | 0.82 | GCGR (0.85) | GCGRALDH1A1HPGDNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | claimed |
| EP-1140823-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-10 | — | — | EP | claimed |
| WO-2000039088-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-06 | — | — | WO | claimed |
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |