Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 12/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24324832 | 0.84 | SPHK1 (0.64) | SPHK1SPHK2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL19234510 | 0.80 | SPHK1 (0.56) | SPHK1ALDH1A1CYP1A2NPC1RAB9A | |
| SCHEMBL20715479 | 0.79 | MAPT (0.58) | SPHK1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20715478 | 0.79 | MAPT (0.58) | SPHK1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL12310783 | 0.78 | NPC1 (0.51) | MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8712090 | 0.78 | NPC1 (0.51) | MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25563421 | 0.75 | TERT (0.53) | MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL1311924 | 0.75 | SPHK1 (1.00) | SPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL1312105 | 0.75 | SPHK1 (1.00) | SPHK1SPHK2S1PR1S1PR3 | |
| SCHEMBL1313131 | 0.75 | SPHK1 (1.00) | SPHK1SPHK2S1PR1S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023073115-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-04 | — | — | WO | disclosed |