Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 7/20 | 0.56 |
| ▸ | CRHBP | P24387 | 1/20 | 0.54 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.54 |
| ▸ | SRC | P12931 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24324832 | 0.87 | SPHK1 (0.64) | SPHK1RAB9ASMN1; SMN2NPC1HDAC3 | |
| SCHEMBL20715478 | 0.85 | MAPT (0.58) | SPHK1CRHBPCRHR2RAB9ASMN1; SMN2 | |
| SCHEMBL20715479 | 0.85 | MAPT (0.58) | SPHK1CRHBPCRHR2RAB9ASMN1; SMN2 | |
| SCHEMBL25562017 | 0.85 | TERT (0.54) | SPHK1CRHBPCRHR2SRCRAB9A | |
| SCHEMBL10223253 | 0.82 | CRHBP (0.59) | CRHBPCRHR2SRCRAB9ASMN1; SMN2 | |
| SCHEMBL370590 | 0.81 | CRHBP (0.59) | SPHK1CRHBPCRHR2SRCRAB9A | |
| SCHEMBL26464767 | 0.80 | SPHK1 (0.60) | SPHK1RAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL19234512 | 0.80 | SPHK1 (0.69) | SPHK1CRHBPCRHR2SRCRAB9A | |
| SCHEMBL25069090 | 0.79 | KMT2A (0.57) | RAB9ASMN1; SMN2NPC1KMT2AMEN1 | |
| SCHEMBL8972648 | 0.79 | NPC1 (0.53) | RAB9ASMN1; SMN2NPC1KMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017136943-A1 | SOMATOSTATIN RECEPTOR ANTAGONIST COMPOUNDS AND METHODS OF USING THE SAME | CDRD VENTURES INC. (CA) | 2017-08-17 | — | — | WO | disclosed |