Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 4/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11453034 | 0.83 | CSNK2A1 (0.36) | PTPN1DHFRCSNK2A1KDM4CPDE4B | |
| SCHEMBL11464250 | 0.78 | KMT2A (0.37) | CSNK2A1PDE4BPDE4APDE4CPDE4D | |
| SCHEMBL2648241 | 0.78 | KDM4C (0.38) | PTPN1DHFRKDM4CPDE4BMEN1 | |
| SCHEMBL10071126 | 0.73 | PTPN1 (0.41) | PTPN1DHFRPDE4B | |
| SCHEMBL13478345 | 0.73 | TSHR (0.38) | CSNK2A1PDE4BSLC6A3 | |
| SCHEMBL11455772 | 0.73 | CSNK2A1 (0.43) | CSNK2A1PDE4BSLC6A3 | |
| SCHEMBL12429188 | 0.72 | SLC6A4 (0.44) | CSNK2A1KDM4CSLC6A3L3MBTL1 | |
| SCHEMBL16695147 | 0.71 | LMNA (0.43) | CSNK2A1PDE4BMEN1KMT2A | |
| SCHEMBL8317291 | 0.71 | CSNK2A1 (0.44) | PTPN1DHFRCSNK2A1PDE4BPDE4A | |
| SCHEMBL7167776 | 0.71 | CSNK2A1 (0.41) | PTPN1CSNK2A1PDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6613942-B1 | Nonpeptide; 4-hydroxy benzoic acid hydrazides | NOVO NORDISK A/S (DK) | 2003-09-02 | — | — | US | disclosed |
| EP-1140823-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039088-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 2000-07-06 | — | — | WO | disclosed |