Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | HTR6 | P50406 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.46 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
| ▸ | HTR3B | O95264 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10036263 | 0.90 | MAPT (0.54) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6606828 | 0.88 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL31267415 | 0.88 | ALDH1A1 (0.60) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL30306155 | 0.87 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL10036436 | 0.87 | ALDH1A1 (0.52) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL25797050 | 0.87 | MAPT (0.59) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL17630806 | 0.86 | SLC6A5 (0.53) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL16305338 | 0.85 | ALDH1A1 (0.55) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL574625 | 0.84 | MAPT (0.49) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 | |
| SCHEMBL574624 | 0.84 | MAPT (0.49) | ALDH1A1MAPTSMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230138863-A1 | SUBSTITUTED DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND AND A COMPOSITION CONTAINING THE COMPOUND AND USE THEREOF | SHENZHEN TARGETRX, INC. (CN) | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230138863-A1 | SUBSTITUTED DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND AND A COMPOSITION CONTAINING THE COMPOUND AND USE THEREOF | FLT3, AXL, ABL1 | ALDH1A1 2607/4885MAPT 2354/4885SMN1; SMN2 3406/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.