Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.63 |
| ▸ | NR1H2 | P55055 | 5/20 | 0.59 |
| ▸ | NR1H3 | Q13133 | 5/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.58 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.58 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.49 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17279684 | 0.90 | NR1H2 (0.67) | ATAD2NR1H2NR1H3ADORA2AADORA1 | |
| SCHEMBL26478149 | 0.85 | ATAD2 (0.68) | ATAD2NR1H2NR1H3ADORA2AADORA1 | |
| SCHEMBL15025693 | 0.83 | NR1H2 (0.73) | ATAD2NR1H2NR1H3ADORA2AADORA1 | |
| SCHEMBL15117068 | 0.82 | KDM4E (0.67) | NR1H2NR1H3ADORA2AADORA1NPC1 | |
| SCHEMBL1505403 | 0.81 | NR1H2 (0.59) | NR1H2NR1H3ADORA2AADORA1NPC1 | |
| SCHEMBL29035880 | 0.80 | NR1H2 (0.89) | ATAD2NR1H2NR1H3ADORA2AADORA1 | |
| SCHEMBL30149870 | 0.80 | NR1H2 (0.89) | ATAD2NR1H2NR1H3ADORA2AADORA1 | |
| SCHEMBL1505282 | 0.80 | NR1H2 (0.54) | NR1H2NR1H3ADORA2AADORA1NPC1 | |
| SCHEMBL17279794 | 0.79 | NR1H2 (0.86) | ATAD2NR1H2NR1H3ADORA2AADORA1 | |
| SCHEMBL6578742 | 0.78 | NR1H2 (0.67) | ATAD2NR1H2NR1H3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023073115-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-04 | — | — | WO | disclosed |
| EP-4173485-A1 | PROTEIN AGGREGATION INHIBITING COMPOUNDS FOR PLANT DISEASE CONTROL | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2023-05-03 | — | — | EP | disclosed |