Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ATP2A2 | P16615 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | ATP2A3 | Q93084 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17813862 | 0.83 | CA2 (0.36) | KDM4ECA1CA2ALDH1A1CYP1A2 | |
| SCHEMBL17808316 | 0.79 | CA1 (0.36) | KDM4ECA1CA2ALDH1A1CYP1A2 | |
| SCHEMBL21719496 | 0.78 | KDM4E (0.36) | KDM4ECA1CA2ALDH1A1ALOX15 | |
| SCHEMBL13990719 | 0.78 | CA2 (0.44) | KDM4ECA1CA2ALDH1A1CYP1A2 | |
| SCHEMBL18699198 | 0.75 | CA1 (0.33) | CA1CA2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL22950665 | 0.72 | NNMT (0.38) | CA1CA2ALDH1A1ALOX15LMNA | |
| SCHEMBL4278709 | 0.71 | RECQL (0.50) | KDM4EALDH1A1CYP1A2CYP2C19RECQL | |
| SCHEMBL25209469 | 0.70 | KDM4E (0.39) | KDM4ECA2ALDH1A1CYP1A2CYP2C19 | |
| SCHEMBL20610132 | 0.70 | KDM4E (0.39) | KDM4EALDH1A1CYP1A2CYP2C19RECQL | |
| SCHEMBL15941543 | 0.70 | MAPT (0.43) | KDM4EALDH1A1CYP1A2CYP2C19LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230136177-A1 | IMMUNOMODULATING O-HET/ARYL AZALIDES | ZOETIS SERVICES LLC | 2023-05-04 | — | — | US | disclosed |
| US-20230136177-A1 | IMMUNOMODULATING O-HET/ARYL AZALIDES | ZOETIS SERVICES LLC | 2023-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230136177-A1 | IMMUNOMODULATING O-HET/ARYL AZALIDES | IL2, MALT1, IL2RA | KDM4E 652/4885CA1 4120/4885CA2 4675/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.