SCHEMBL26465909

SCHEMBL26465909

CC(=O)c1cccc2c1-c1ccccc1C2O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.54
PDK2 Q15119 1/20 0.48
POLB P06746 1/20 0.43
DRD2 P14416 1/20 0.41
NPC1 O15118 1/20 0.40
HNF4A P41235 1/20 0.40
HTR2B P41595 3/20 0.39
MAPT P10636 4/20 0.39
MEN1 O00255 3/20 0.39
KMT2A Q03164 3/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39
MAPK10 P53779 1/20 0.39
PTK2B Q14289 1/20 0.39
NCOA1 Q15788 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
NCOA3 Q9Y6Q9 1/20 0.39
ALDH1A1 P00352 3/20 0.39
MYC P01106 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31670369 0.80 KDM4E (0.69) KDM4EPDK2MAPTMEN1KMT2A
SCHEMBL8750096 0.74 HTR2B (0.51) KDM4EPDK2HTR2BMAPTMEN1
SCHEMBL28172796 0.72 MAOA (0.43) KDM4EPDK2POLBHTR2BMAPT
SCHEMBL5520562 0.70 MAPT (0.47) KDM4EPDK2HTR2BMAPTMEN1
SCHEMBL10968334 0.70 HTR2B (0.59) KDM4EPDK2POLBDRD2NPC1
SCHEMBL978600 0.70 KDM4C (0.50) KDM4EPDK2POLBMAPTMEN1
SCHEMBL29376368 0.70 MAOA (0.52) KDM4EPOLBHTR2BMAPTMEN1
SCHEMBL29884836 0.70 MAOA (0.52) KDM4EPOLBHTR2BMAPTMEN1
SCHEMBL216862 0.70 MAOA (0.52) KDM4EPOLBHTR2BMAPTMEN1
SCHEMBL11147739 0.69 ALDH1A1 (0.70) KDM4EPOLBNPC1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023075016-A1 NOVEL COMPOUND AND COMPOSITION FOR PREVENTING OR TREATING NEUROINFLAMMATORY BRAIN DISEASES COMPRISING SAME AS ACTIVE INGREDIENT 한국해양과학기술원 2023-05-04 WO disclosed